M-Xylene

M-Xylene

SCHEMBL17907456

Cc1cccc(C)c1.NC(=O)c1ccc2ccccc2c1C=O

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 3/20 0.46
RAB9A P51151 2/20 0.44
NPC1 O15118 1/20 0.44
GAA P10253 3/20 0.43
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
KDM4E B2RXH2 4/20 0.42
ALDH1A1 P00352 3/20 0.42
HPGD P15428 2/20 0.42
PARP1 P09874 3/20 0.41
MAPT P10636 2/20 0.41
LMNA P02545 2/20 0.41
GLA P06280 1/20 0.41
ALOX15 P16050 1/20 0.41
CASP1 P29466 1/20 0.41
HTT P42858 1/20 0.41
CASP7 P55210 1/20 0.41
HSD17B10 Q99714 1/20 0.41
CYP1A2 P05177 1/20 0.40
CYP2C9 P11712 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
P-Xylene SCHEMBL17907471 0.90 ERN1 (0.50) ERN1RAB9ANPC1GAAMEN1
SCHEMBL157600 0.88 ERN1 (0.58) ERN1RAB9ANPC1GAAMEN1
SCHEMBL14837756 0.87 ERN1 (0.56) ERN1RAB9ANPC1GAAMEN1
SCHEMBL6244290 0.76 ERN1 (0.58) ERN1RAB9ANPC1GAAKMT2A
SCHEMBL11775594 0.75 PADI4 (0.53) ERN1GAAMEN1KMT2AKDM4E
SCHEMBL547877 0.74 WDR5 (0.61) ERN1RAB9ANPC1GAAMEN1
SCHEMBL5153416 0.72 TSHR (0.50) RAB9AGAAMEN1KMT2AKDM4E
SCHEMBL19873094 0.72 ERN1 (0.57) ERN1GAAKDM4EALDH1A1HPGD
SCHEMBL2820618 0.72 ERN1 (0.53) ERN1RAB9ANPC1GAAMEN1
Glucuronate SCHEMBL3663071 0.71 ERN1 (0.40) ERN1RAB9ANPC1GAAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11254082-B2 Multi-layer tube UBE INDUSTRIES, LTD. (JP) 2022-02-22 US disclosed
US-10663092-B2 Multilayer tube UBE INDUSTRIES, LTD. (JP) 2020-05-26 US disclosed
EP-3042758-B1 LAMINATED TUBE UBE INDUSTRIES (JP) 2020-05-06 EP disclosed
EP-3461631-A1 MULTILAYER TUBE Ube Industries, Ltd. (JP) 2019-04-03 EP disclosed
EP-3192650-B1 LAYERED TUBE UBE INDUSTRIES (JP) 2019-01-23 EP disclosed
US-20170261133-A1 MULTILAYER TUBE UBE INDUSTRIES, LTD. (JP) 2017-09-14 US disclosed
EP-3192650-A1 LAYERED TUBE UBE Industries, Ltd. (JP) 2017-07-19 EP disclosed
US-20160214343-A1 MULTI-LAYER TUBE UBE INDUSTRIES, LTD. (JP) 2016-07-28 US disclosed
EP-3042758-A1 LAMINATED TUBE UBE Industries, Ltd. (JP) 2016-07-13 EP disclosed