P-Xylene

P-Xylene

SCHEMBL17907471

Cc1ccc(C)cc1.NC(=O)c1ccc2ccccc2c1C=O

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 2/20 0.50
KMT2A Q03164 2/20 0.45
MEN1 O00255 1/20 0.45
KDM4A O75164 1/20 0.45
CTDSP1 Q9GZU7 1/20 0.45
KDM4C Q9H3R0 1/20 0.45
CYP1A2 P05177 1/20 0.43
MAPT P10636 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
RRM1 P23921 2/20 0.43
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
GAA P10253 2/20 0.41
KDM4E B2RXH2 2/20 0.41
USP2 O75604 1/20 0.41
ALDH1A1 P00352 1/20 0.41
HPGD P15428 1/20 0.41
GRIN2D O15399 1/20 0.40
GRIN3B O60391 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL157600 0.92 ERN1 (0.58) ERN1KMT2AMEN1CYP1A2MAPT
SCHEMBL14837756 0.91 ERN1 (0.56) ERN1KMT2AMEN1CYP1A2MAPT
M-Xylene SCHEMBL17907456 0.90 ERN1 (0.46) ERN1KMT2AMEN1CYP1A2MAPT
SCHEMBL6244290 0.79 ERN1 (0.58) ERN1KMT2ACYP1A2MAPTCYP2C9
SCHEMBL547877 0.77 WDR5 (0.61) ERN1KMT2AMEN1CYP1A2MAPT
SCHEMBL5153416 0.75 TSHR (0.50) KMT2AMEN1CYP1A2RAB9AGAA
SCHEMBL2820618 0.75 ERN1 (0.53) ERN1KMT2AMEN1CYP1A2MAPT
SCHEMBL11775594 0.75 PADI4 (0.53) ERN1KMT2AMEN1MAPTCYP2C9
Glucuronate SCHEMBL3663071 0.74 ERN1 (0.40) ERN1KMT2AMEN1CYP1A2MAPT
SCHEMBL15776037 0.74 CYP1B1 (0.41) ERN1KMT2AMEN1MAPTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11254082-B2 Multi-layer tube UBE INDUSTRIES, LTD. (JP) 2022-02-22 US disclosed
US-10663092-B2 Multilayer tube UBE INDUSTRIES, LTD. (JP) 2020-05-26 US disclosed
EP-3042758-B1 LAMINATED TUBE UBE INDUSTRIES (JP) 2020-05-06 EP disclosed
EP-3461631-A1 MULTILAYER TUBE Ube Industries, Ltd. (JP) 2019-04-03 EP disclosed
EP-3192650-B1 LAYERED TUBE UBE INDUSTRIES (JP) 2019-01-23 EP disclosed
US-20170261133-A1 MULTILAYER TUBE UBE INDUSTRIES, LTD. (JP) 2017-09-14 US disclosed
EP-3192650-A1 LAYERED TUBE UBE Industries, Ltd. (JP) 2017-07-19 EP disclosed
US-20160214343-A1 MULTI-LAYER TUBE UBE INDUSTRIES, LTD. (JP) 2016-07-28 US disclosed
EP-3042758-A1 LAMINATED TUBE UBE Industries, Ltd. (JP) 2016-07-13 EP disclosed