Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 3/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL754366 | 0.83 | MAPT (0.46) | MAOBKMT2AMEN1ALDH1A1 | |
| SCHEMBL17907484 | 0.82 | BACE1 (0.37) | MAOBKMT2AMEN1POLBPKM | |
| SCHEMBL754365 | 0.73 | PPARG (0.49) | MAOBKMT2AMEN1POLBPKM | |
| SCHEMBL754649 | 0.71 | MAOB (0.49) | MAOB | |
| SCHEMBL25190860 | 0.65 | SLC5A1 (0.61) | MAOBNFKB1NFKB2RELAKMT2A | |
| SCHEMBL31088177 | 0.65 | BACE1 (0.56) | MAOBKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL31088175 | 0.65 | BACE1 (0.56) | MAOBKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL25205681 | 0.63 | NFKB1 (0.63) | MAOBNFKB1NFKB2RELAKMT2A | |
| SCHEMBL30383093 | 0.63 | NFKB1 (0.63) | MAOBNFKB1NFKB2RELAKMT2A | |
| SCHEMBL25205679 | 0.63 | NFKB1 (0.63) | MAOBNFKB1NFKB2RELAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3042894-A1 | ANTIVIRAL AGENT | SHIONOGI & CO., LTD. (JP) | 2016-07-13 | — | — | EP | disclosed |