Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | DUT | P33316 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9267566 | 0.79 | CYP3A4 (0.42) | BACE1MAPTHPGDDUTCA12 | |
| SCHEMBL754031 | 0.74 | KDM4E (0.45) | BACE1MAPT | |
| SCHEMBL10819498 | 0.72 | CA12 (0.33) | BACE1DUTCA12CA1CA9 | |
| SCHEMBL9270997 | 0.71 | CA12 (0.44) | MAPTHPGDDUTCA12CA1 | |
| SCHEMBL764275 | 0.71 | DAO (0.62) | — | |
| SCHEMBL30688991 | 0.70 | DUT (0.34) | BACE1DUTCA12CA1CA9 | |
| SCHEMBL19215535 | 0.70 | NQO1 (0.36) | HPGD | |
| SCHEMBL13045060 | 0.70 | CA12 (0.35) | MAPTHPGDCA12CA1CA9 | |
| SCHEMBL10819492 | 0.70 | MAPT (0.32) | MAPTHPGDCA12CA1CA9 | |
| SCHEMBL1157878 | 0.69 | CA12 (0.34) | MAPTHPGDCA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3042894-A1 | ANTIVIRAL AGENT | SHIONOGI & CO., LTD. (JP) | 2016-07-13 | — | — | EP | disclosed |