SCHEMBL754031

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16925513	0.79	DUT (0.32)	KDM4EALDH1A1POLBTDP1L3MBTL1
	SCHEMBL11464684	0.78	ELANE (0.51)	KDM4EALDH1A1POLBTDP1L3MBTL1
	SCHEMBL3564109	0.77	MMP2 (0.40)	KDM4EALDH1A1POLBTDP1L3MBTL1
	SCHEMBL755692	0.77	LMNA (0.38)	KDM4EALDH1A1POLBTEAD4MEN1
	SCHEMBL3558568	0.75	KDM4E (0.65)	KDM4EALDH1A1POLBTDP1L3MBTL1
	SCHEMBL9267566	0.75	CYP3A4 (0.42)	KDM4EALDH1A1TDP1MEN1MAPT
	SCHEMBL13045060	0.74	CA12 (0.35)	MAPT
	SCHEMBL10819492	0.74	MAPT (0.32)	MAPT
	SCHEMBL16921604	0.74	KDM4E (0.59)	KDM4EALDH1A1POLBTDP1L3MBTL1
	SCHEMBL10819498	0.74	CA12 (0.33)	BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.