Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 10/20 | 1.00 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.45 |
| ▸ | QPCT | Q16769 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL455344 | 0.83 | IDO1 (0.78) | IDO1MAPTKDM4EGAAALDH1A1 | |
| SCHEMBL24894101 | 0.82 | IDO1 (0.70) | IDO1MAPTGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL2235410 | 0.81 | ALDH1A1 (0.69) | IDO1MAPTKDM4EGAAALDH1A1 | |
| SCHEMBL5521712 | 0.80 | IDO1 (0.67) | IDO1MAPTKDM4EGAAALDH1A1 | |
| SCHEMBL5432263 | 0.79 | MAPT (0.69) | IDO1MAPTGAAALDH1A1MEN1 | |
| SCHEMBL455272 | 0.78 | IDO1 (0.64) | IDO1MAPTKDM4EGAAALDH1A1 | |
| SCHEMBL455323 | 0.75 | GAA (0.74) | IDO1MAPTKDM4EGAAALDH1A1 | |
| SCHEMBL1642748 | 0.75 | IDO1 (0.67) | IDO1MAPTKDM4EGAAALDH1A1 | |
| SCHEMBL14725327 | 0.74 | IDO1 (0.58) | IDO1MAPTGAAALDH1A1MEN1 | |
| SCHEMBL9036606 | 0.74 | IDO1 (1.00) | IDO1MAPTKDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016111658-A1 | SYNTHESIS OF THIOSEMICARBAZONE DERIVATIVES COMPRISING SULPHONAMIDE GROUP WITH POTENTIAL ANTICONVULSANT ACTIVITY | IYIDOGAN AYSEGUL (TR) | 2016-07-14 | — | — | WO | claimed |
| WO-2016111658-A1 | SYNTHESIS OF THIOSEMICARBAZONE DERIVATIVES COMPRISING SULPHONAMIDE GROUP WITH POTENTIAL ANTICONVULSANT ACTIVITY | IYIDOGAN AYSEGUL (TR) | 2016-07-14 | — | — | WO | disclosed |