Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.43 |
| ▸ | IDH1 | O75874 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14725326 | 0.80 | ALDH1A1 (0.63) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL2235410 | 0.78 | ALDH1A1 (0.69) | IDO1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL2237481 | 0.76 | CA1 (0.60) | IDO1ALDH1A1CA12CA1CA2 | |
| SCHEMBL24894101 | 0.75 | IDO1 (0.70) | IDO1ALDH1A1MAPTALOX12HTT | |
| SCHEMBL14725325 | 0.74 | CA1 (0.50) | ALDH1A1MEN1KMT2AMAPK1MAPT | |
| SCHEMBL17913053 | 0.74 | IDO1 (1.00) | IDO1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL4455223 | 0.72 | PTPRB (0.48) | ALDH1A1MEN1KMT2AHTTALOX15 | |
| SCHEMBL27460196 | 0.72 | ALDH1A1 (0.52) | ALDH1A1KMT2AMAPTALOX12GAA | |
| SCHEMBL14799102 | 0.71 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2AMAPK1MAPT | |
| SCHEMBL17079615 | 0.70 | ALDH1A1 (0.68) | IDO1ALDH1A1MEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130053392-A1 | CARBONIC ANHYDRASE INHIBITORS | UNIVERSITETET I OSLO (NO) | 2013-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130053392-A1 | CARBONIC ANHYDRASE INHIBITORS | CA9, CA2, CA4 | IDO1 1310/4885ALDH1A1 682/4885MEN1 2899/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.