Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIA | P62937 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17913088 | 0.95 | PPIA (0.64) | PPIAALDH1A1ALOX12MEN1KMT2A | |
| SCHEMBL17913070 | 0.91 | PPIA (0.59) | PPIAALDH1A1ALOX12MEN1KMT2A | |
| SCHEMBL17913097 | 0.91 | PPIA (0.59) | PPIAALDH1A1ALOX12MEN1KMT2A | |
| SCHEMBL17913038 | 0.89 | FAAH (0.55) | ALDH1A1ALOX12MEN1KMT2AFAAH | |
| SCHEMBL17913049 | 0.85 | GAA (0.56) | ALDH1A1MAPTPOLBLMNAGAA | |
| SCHEMBL17913101 | 0.85 | GAA (0.56) | ALDH1A1MAPTPOLBLMNAGAA | |
| SCHEMBL17913041 | 0.81 | ALDH1A1 (0.57) | ALDH1A1ALOX12MEN1KMT2AFAAH | |
| SCHEMBL17913062 | 0.79 | TDP1 (0.69) | ALDH1A1ALOX12MEN1KMT2AMAOB | |
| SCHEMBL17913043 | 0.79 | ALDH1A1 (0.60) | PPIAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL17913042 | 0.79 | ALDH1A1 (0.60) | PPIAALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016111658-A1 | SYNTHESIS OF THIOSEMICARBAZONE DERIVATIVES COMPRISING SULPHONAMIDE GROUP WITH POTENTIAL ANTICONVULSANT ACTIVITY | IYIDOGAN AYSEGUL (TR) | 2016-07-14 | — | — | WO | disclosed |