Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 4/20 | 0.42 |
| ▸ | MAPK12 | P53778 | 4/20 | 0.42 |
| ▸ | MAPK11 | Q15759 | 4/20 | 0.42 |
| ▸ | GCGR | P47871 | 1/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17914765 | 0.99 | NOTUM (0.44) | NOTUMMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL17914761 | 0.93 | ADORA2A (0.41) | DHODHALDH1A1KDM4ELMNAADORA2A | |
| SCHEMBL17914788 | 0.92 | DHODH (0.47) | NOTUMMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL17915344 | 0.92 | ALDH1A1 (0.45) | MAPK14MAPK13MAPK12MAPK11GCGR | |
| SCHEMBL17915297 | 0.92 | ALDH1A1 (0.45) | MAPK14MAPK13MAPK12MAPK11GCGR | |
| SCHEMBL17915169 | 0.92 | MAPT (0.43) | MAPK14MAPK13MAPK12MAPK11GCGR | |
| SCHEMBL17914713 | 0.91 | MAPK14 (0.47) | NOTUMMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL17914766 | 0.91 | ADORA2A (0.42) | DHODHALDH1A1KDM4ELMNAADORA2A | |
| SCHEMBL17915291 | 0.91 | MAPT (0.44) | MAPK14MAPTALDH1A1HPGDKDM4E | |
| SCHEMBL17915178 | 0.90 | DHODH (0.47) | NOTUMMAPK14MAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160204357-A1 | POLYCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME | HEESUNG MATERIAL LTD. (KR) | 2016-07-14 | — | — | US | disclosed |
| US-20160204357-A1 | POLYCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME | HEESUNG MATERIAL LTD. (KR) | 2016-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160204357-A1 | POLYCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME | NOTUM, ORC3, PPOX | NOTUM 1/4885MAPK14 4499/4885MAPK13 4420/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.