SCHEMBL17916643

SCHEMBL17916643

FC(F)C(F)(F)C(F)(F)C(F)(F)CCOCCC(F)(F)C(F)(F)C(F)(F)C(F)F

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.34
TSHR P16473 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
LMNA P02545 1/20 0.32
HPGD P15428 1/20 0.32
XBP1 P17861 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2C19 P33261 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26626978 0.87 KDM4E (0.31) KDM4ETSHRTDP1
SCHEMBL14029098 0.81 THRB (0.33) LMNAHPGDXBP1SMN1; SMN2NPSR1
SCHEMBL25980486 0.81 PRKD3 (0.32)
SCHEMBL29636858 0.78 TSHR (0.44) TSHRTDP1SMN1; SMN2
SCHEMBL24098416 0.76 CYP1A2 (0.37) KDM4ETSHRTDP1CYP1A2CYP2C19
SCHEMBL25980467 0.76 PRKD3 (0.31) CYP1A2CYP2C19
SCHEMBL497555 0.75 LMNA (0.43) KDM4ETSHRTDP1LMNAHPGD
SCHEMBL25980491 0.74 CYP1A2 (0.32) TSHRCYP1A2CYP2C19
SCHEMBL16572039 0.74
SCHEMBL25979563 0.74 CYP1A2 (0.39) KDM4ETSHRTDP1CYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160200068-A1 METHOD FOR FABRICATING COLUMNAR OR LAMELLAR STRUCTURES OF ORGANIC MOLECULES ALIGNED INTO LARGE-AREA SINGLE DOMAIN KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2016-07-14 US disclosed