Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | TLR2 | O60603 | 2/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.47 |
| ▸ | MDM4 | O15151 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13495919 | 1.00 | KMT2A (0.61) | KMT2ATLR2SIRT2MDM4TP53 | |
| SCHEMBL16217863 | 0.94 | KMT2A (0.58) | KMT2ATLR2 | |
| SCHEMBL30265401 | 0.93 | KMT2A (0.53) | KMT2ATLR2SIRT2MDM2 | |
| SCHEMBL29423637 | 0.91 | KMT2A (0.53) | KMT2ATLR2MDM4TP53MDM2 | |
| SCHEMBL22691905 | 0.91 | KMT2A (0.53) | KMT2ATLR2MDM4TP53MDM2 | |
| SCHEMBL12971617 | 0.91 | KMT2A (0.61) | KMT2ATLR2MDM4TP53MDM2 | |
| SCHEMBL12264511 | 0.91 | KMT2A (0.52) | KMT2ATLR2SIRT2MDM4TP53 | |
| SCHEMBL18474877 | 0.90 | KMT2A (0.49) | KMT2ATLR2MDM4TP53MDM2 | |
| SCHEMBL13225950 | 0.90 | TLR2 (0.49) | KMT2ATLR2MDM4TP53MDM2 | |
| SCHEMBL260631 | 0.90 | KMT2A (0.66) | KMT2ATLR2MDM4TP53MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016110577-A1 | CNP PRODRUGS | ASCENDIS PHARMA A/S (DK) | 2016-07-14 | — | — | WO | disclosed |