SCHEMBL12971617

SCHEMBL12971617

CC(=O)C(CCCCNC(=O)OCC1c2ccccc2-c2ccccc21)NC(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.62

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 1/20 0.61
▸ TLR2 O60603 3/20 0.50
▸ MDM2 Q00987 2/20 0.48
▸ MDM4 O15151 1/20 0.46
▸ TP53 P04637 1/20 0.46
▸ CASP3 P42574 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16329206 0.92 KMT2A (0.53) KMT2ATLR2MDM2MDM4TP53
SCHEMBL15750412 0.92 KMT2A (0.53) KMT2ATLR2MDM2MDM4TP53
SCHEMBL31522724 0.92 KMT2A (0.53) KMT2ATLR2MDM2MDM4TP53
SCHEMBL13495919 0.91 KMT2A (0.61) KMT2ATLR2MDM2MDM4TP53
SCHEMBL17919592 0.91 KMT2A (0.61) KMT2ATLR2MDM2MDM4TP53
SCHEMBL30693894 0.91 KMT2A (0.51) KMT2ATLR2MDM2
SCHEMBL178698 0.90 KMT2A (0.66) KMT2ATLR2MDM2MDM4TP53
SCHEMBL260631 0.90 KMT2A (0.66) KMT2ATLR2MDM2MDM4TP53
SCHEMBL178733 0.90 KMT2A (0.66) KMT2ATLR2MDM2MDM4TP53
SCHEMBL29359997 0.90 KMT2A (0.66) KMT2ATLR2MDM2MDM4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100331489-A1 BRANCHED WATER-SOLUBLE POLYMERS AND THEIR CONJUGATES BIOGENERIX AG (DE) 2010-12-30 — — US disclosed
US-7803777-B2 Branched water-soluble polymers and their conjugates BIOGENERIX AG (DE) 2010-09-28 — — US disclosed
US-20080319183-A1 Branched Polymeric Sugars and Nucleotides Thereof NEOSE TECHNOLOGIES, INC. (US) 2008-12-25 — — US disclosed
US-20070032405-A1 Branched water-soluble polymers and their conjugates NEOSE TECHNOLOGIES, INC. (US) 2007-02-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080319183-A1 Branched Polymeric Sugars and Nucleotides Thereof GALE, NUDT14, GNE KMT2A 3676/4885TLR2 440/4885MDM2 2963/4885
US-20100331489-A1 BRANCHED WATER-SOLUBLE POLYMERS AND THEIR CONJUGATES SLC7A5, SLC43A1, SLC7A1 KMT2A 3771/4885TLR2 904/4885MDM2 1844/4885
US-20070032405-A1 Branched water-soluble polymers and their conjugates SLC7A5, SLC43A1, SLC7A1 KMT2A 3771/4885TLR2 904/4885MDM2 1844/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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