Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.33 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | TSHR | P16473 | 5/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL1792008 | 1.00 | ALDH1A1 (0.38) | ALDH1A1TSHRTDP1ALOX12CA1 | |
| SCHEMBL169051 | 0.96 | ALDH1A1 (0.40) | ALDH1A1TSHRTDP1ALOX12CA1 | |
| Hydrochloric Acid SCHEMBL124215 | 0.92 | ALDH1A1 (0.38) | ALDH1A1TSHRTDP1ALOX12CA1 | |
| Iodide SCHEMBL1794149 | 0.92 | ALDH1A1 (0.38) | ALDH1A1TSHRTDP1ALOX12CA1 | |
| Iodide SCHEMBL29124326 | 0.92 | ALDH1A1 (0.38) | ALDH1A1TSHRTDP1ALOX12CA1 | |
| SCHEMBL3283587 | 0.92 | ALDH1A1 (0.38) | ALDH1A1TSHRTDP1ALOX12CA1 | |
| Iodide SCHEMBL8979570 | 0.92 | ALDH1A1 (0.38) | ALDH1A1TSHRTDP1ALOX12CA1 | |
| Iodide SCHEMBL1794148 | 0.92 | ALDH1A1 (0.38) | ALDH1A1TSHRTDP1ALOX12CA1 | |
| Water SCHEMBL11743637 | 0.92 | ALDH1A1 (0.38) | ALDH1A1TSHRTDP1ALOX12CA1 | |
| Hydrochloric Acid SCHEMBL6912014 | 0.92 | ALDH1A1 (0.38) | ALDH1A1TSHRTDP1ALOX12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118620200-A | Polyester amide based on furan ring and preparation method thereof | 中国科学技术大学 | 2024-09-10 | — | — | CN | claimed |
| CN-118580453-A | Furan ring-based polyurethane, polyurethane emulsion, and preparation methods and applications thereof | 中国科学技术大学 | 2024-09-03 | — | — | CN | claimed |
| CN-117209740-A | Preparation method of poly (ethylene 2, 5-furandicarboxylate) | 浙江糖能科技有限公司 | 2023-12-12 | — | — | CN | claimed |
| EP-2499180-A2 | POLYOXAZOLIDONE RESINS | Dow Global Technologies LLC (US) | 2012-09-19 | — | — | EP | claimed |
| US-20120214958-A1 | POLYOXAZOLIDONE RESINS | BLUE CUBE IP LLC | 2012-08-23 | — | — | US | claimed |
| WO-2011059633-A2 | POLYOXAZOLIDONE RESINS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2011-05-19 | — | — | WO | claimed |
| US-5126406-A | Polyoxazolidones of good heat resistance and impact strength | NIPPON PAINT CO., LTD. (JP) | 1992-06-30 | — | — | US | claimed |
| EP-0444956-A2 | Thermosetting resin composition and article obtained therefrom | NIPPON PAINT CO., LTD. (JP) | 1991-09-04 | — | — | EP | claimed |
| CN-115842112-B | Secondary battery, battery module, battery pack and power utilization device thereof | 宁德时代新能源科技股份有限公司 | 2025-01-03 | — | — | CN | disclosed |
| CN-118795725-A | Semiconductor photoresist composition and method of forming pattern using the same | 三星SDI株式会社 | 2024-10-18 | — | — | CN | disclosed |
| US-20240345477-A1 | SEMICONDUCTOR PHOTORESIST COMPOSITION AND METHOD OF FORMING PATTERNS USING THE COMPOSITION | SAMSUNG SDI CO., LTD. (KR) | 2024-10-17 | — | — | US | disclosed |
| CN-118620200-A | Polyester amide based on furan ring and preparation method thereof | 中国科学技术大学 | 2024-09-10 | — | — | CN | disclosed |
| CN-118580453-A | Furan ring-based polyurethane, polyurethane emulsion, and preparation methods and applications thereof | 中国科学技术大学 | 2024-09-03 | — | — | CN | disclosed |
| CN-117209740-A | Preparation method of poly (ethylene 2, 5-furandicarboxylate) | 浙江糖能科技有限公司 | 2023-12-12 | — | — | CN | disclosed |
| WO-2011063327-A2 | TOUGHENED EPOXY RESIN FORMULATIONS | DOW GLOBAL TECHNOLOGIES LLC. (US) | 2011-05-26 | — | — | WO | disclosed |
| EP-2325876-A2 | Epoxy resin formulations for underfill applications | DOW Global Technologies (US) | 2011-05-25 | — | — | EP | disclosed |
| WO-2011059633-A2 | POLYOXAZOLIDONE RESINS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2011-05-19 | — | — | WO | disclosed |
| EP-0444956-B1 | Thermosetting resin composition and article obtained therefrom | NIPPON PAINT CO LTD (JP) | 1996-10-23 | — | — | EP | disclosed |
| US-5126406-A | Polyoxazolidones of good heat resistance and impact strength | NIPPON PAINT CO., LTD. (JP) | 1992-06-30 | — | — | US | disclosed |
| EP-0444956-A2 | Thermosetting resin composition and article obtained therefrom | NIPPON PAINT CO., LTD. (JP) | 1991-09-04 | — | — | EP | disclosed |