Iodide

Iodide

SCHEMBL8979570

I.I.c1ccc([Sb](c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG

The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE known ✓ P22303 1/20 0.33
ALDH1A1 P00352 5/20 0.38
TSHR P16473 5/20 0.33
TDP1 Q9NUW8 5/20 0.33
ALOX12 P18054 3/20 0.33
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA9 Q16790 2/20 0.33
CA12 O43570 1/20 0.33
GLA P06280 1/20 0.33
CA3 P07451 1/20 0.33
CA4 P22748 1/20 0.33
CA14 Q9ULX7 1/20 0.33
LMNA P02545 1/20 0.33
CA7 P43166 1/20 0.33
HSD17B10 Q99714 3/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
MGLL Q99685 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iodide SCHEMBL9007084 1.00 ALDH1A1 (0.38) ALDH1A1TSHRTDP1ALOX12CA1
Iodide SCHEMBL29124326 1.00 ALDH1A1 (0.38) ALDH1A1TSHRTDP1ALOX12CA1
Iodide SCHEMBL1794149 1.00 ALDH1A1 (0.38) ALDH1A1TSHRTDP1ALOX12CA1
SCHEMBL169051 0.96 ALDH1A1 (0.40) ALDH1A1TSHRTDP1ALOX12CA1
Hydrochloric Acid SCHEMBL6912014 0.92 ALDH1A1 (0.38) ALDH1A1TSHRTDP1ALOX12CA1
Water SCHEMBL11743637 0.92 ALDH1A1 (0.38) ALDH1A1TSHRTDP1ALOX12CA1
Iodide SCHEMBL1794148 0.92 ALDH1A1 (0.38) ALDH1A1TSHRTDP1ALOX12CA1
Hydrochloric Acid SCHEMBL124215 0.92 ALDH1A1 (0.38) ALDH1A1TSHRTDP1ALOX12CA1
SCHEMBL3283587 0.92 ALDH1A1 (0.38) ALDH1A1TSHRTDP1ALOX12CA1
Bromide SCHEMBL1792004 0.92 ALDH1A1 (0.38) ALDH1A1TSHRTDP1ALOX12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5126406-A Polyoxazolidones of good heat resistance and impact strength NIPPON PAINT CO., LTD. (JP) 1992-06-30 US claimed
EP-0444956-A2 Thermosetting resin composition and article obtained therefrom NIPPON PAINT CO., LTD. (JP) 1991-09-04 EP claimed
EP-0444956-B1 Thermosetting resin composition and article obtained therefrom NIPPON PAINT CO LTD (JP) 1996-10-23 EP disclosed
EP-0412759-B1 Heat-curable type resinous composition and moulded article prepared therefrom NIPPON PAINT CO LTD (JP) 1996-05-08 EP disclosed
US-5126406-A Polyoxazolidones of good heat resistance and impact strength NIPPON PAINT CO., LTD. (JP) 1992-06-30 US disclosed
US-5086152-A Complex of organs antimory halide and zinc ralide as catalyst NIPPON PAINT CO., LTD. (JP) 1992-02-04 US disclosed
EP-0444956-A2 Thermosetting resin composition and article obtained therefrom NIPPON PAINT CO., LTD. (JP) 1991-09-04 EP disclosed
EP-0412759-A2 Heat-curable type resinous composition and moulded article prepared therefrom NIPPON PAINT CO., LTD. (JP) 1991-02-13 EP disclosed
EP-0222872-A4 A PROCESS FOR PREPARING A POLYOXAZOLIDONE. DOW CHEMICAL CO (US) 1987-09-07 EP disclosed
EP-0222872-A1 A PROCESS FOR PREPARING A POLYOXAZOLIDONE THE DOW CHEMICAL COMPANY (US) 1987-05-27 EP disclosed
US-4658007-A REACTING A POLYEPOXIDE AND A POLYISOCYANATE USING AN ORGANOANTIMONY IODIDE CATALYST TO SUPRESS TRIMERIZATION THE DOW CHEMICAL COMPANY (US) 1987-04-14 US disclosed
EP-0191092-A4 PROCESS FOR PREPARING POLYMER POLYAHLS. DOW CHEMICAL CO (US) 1987-01-10 EP disclosed
WO-1986006734-A1 A PROCESS FOR PREPARING A POLYOXAZOLIDONE THE DOW CHEMICAL COMPANY (US) 1986-11-20 WO disclosed
EP-0191092-A1 PROCESS FOR PREPARING POLYMER POLYAHLS THE DOW CHEMICAL COMPANY (US) 1986-08-20 EP disclosed
WO-1986001523-A1 PROCESS FOR PREPARING POLYMER POLYAHLS THE DOW CHEMICAL COMPANY (US) 1986-03-13 WO disclosed
US-4574137-A UNSATURATED MONOMER GRAFTED TO POLYMER, HALOGEN CATALYST THE DOW CHEMICAL COMPANY (US) 1986-03-04 US disclosed