Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16063986 | 0.81 | FFAR2 (0.32) | FFAR2 | |
| SCHEMBL22915324 | 0.81 | FFAR2 (0.32) | FFAR2 | |
| SCHEMBL25919388 | 0.77 | GAA (0.31) | — | |
| SCHEMBL28906020 | 0.76 | SLC7A5 (0.39) | — | |
| SCHEMBL18055298 | 0.72 | AAK1 (0.35) | — | |
| SCHEMBL17920111 | 0.72 | CA1 (0.35) | — | |
| SCHEMBL1709947 | 0.72 | CA1 (0.35) | — | |
| SCHEMBL22267902 | 0.72 | AAK1 (0.35) | — | |
| SCHEMBL9915023 | 0.72 | CA1 (0.35) | — | |
| SCHEMBL16022889 | 0.71 | ALDH1A1 (0.46) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016112321-A1 | CYCLOSPORIN DERIVATIVES WHEREIN THE MEBMT SIDECHAIN HAS BEEN CYCLIZED | ALLERGAN, INC. (US) | 2016-07-14 | — | — | WO | disclosed |