Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | DBH | P09172 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | PGR | P06401 | 1/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | HRH1 | P35367 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | CES2 | O00748 | 3/20 | 0.50 |
| ▸ | CES1 | P23141 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28283115 | 0.95 | TDP1 (0.56) | TDP1L3MBTL1KDM4EDBHGAA | |
| SCHEMBL163939 | 0.95 | TDP1 (0.56) | TDP1L3MBTL1KDM4EDBHGAA | |
| Hydrochloric Acid SCHEMBL27519979 | 0.93 | TDP1 (0.54) | TDP1L3MBTL1KDM4EDBHGAA | |
| SCHEMBL27996952 | 0.93 | TDP1 (0.54) | TDP1L3MBTL1KDM4EDBHGAA | |
| Bromide SCHEMBL8414921 | 0.93 | TDP1 (0.54) | TDP1L3MBTL1KDM4EDBHGAA | |
| Acetic Acid SCHEMBL28771195 | 0.91 | TDP1 (0.52) | TDP1L3MBTL1KDM4EDBHGAA | |
| SCHEMBL1792144 | 0.91 | TDP1 (0.52) | TDP1L3MBTL1KDM4EDBHGAA | |
| Formaldehyde SCHEMBL10644284 | 0.91 | TDP1 (0.52) | TDP1L3MBTL1KDM4EDBHGAA | |
| Phenol SCHEMBL14718671 | 0.86 | CES2 (0.50) | TDP1L3MBTL1KDM4EDBHGAA | |
| SCHEMBL16222220 | 0.86 | ALDH1A1 (0.61) | TDP1L3MBTL1KDM4EDBHGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8574311-B2 | Versatile biodegradable elastic polymers featured with dual crosslinking mechanism for biomedical applications | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2013-11-05 | — | — | US | disclosed |
| US-20110124765-A1 | Versatile Biodegradable Elastic Polymers Featured with Dual Crosslinking Mechanism for Biomedical Applications | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2011-05-26 | — | — | US | disclosed |
| WO-2009137715-A2 | VERSATILE BIODEGRADABLE ELASTIC POLYMERS FEATURED WITH DUAL CROSSLINKING MECHANISM FOR BIOMEDICAL APPLICATIONS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2009-11-12 | — | — | WO | disclosed |