SCHEMBL17922798

SCHEMBL17922798

NC(=O)[C@H](CCCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)[C@@H](N)CCCCNC(=O)[C@@H](N)CCCCNC(=O)[C@@H](N)CCCCNC(=O)CCCCCCCCCCCCCCCCC(=O)O)NI

nearest known ligand 0.53

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.53
▸ EPOR P19235 2/20 0.39
▸ NOD1 Q9Y239 2/20 0.38
▸ CD40 P25942 1/20 0.37
▸ CCKAR P32238 4/20 0.37
▸ CCKBR P32239 4/20 0.37
▸ FOLH1 Q04609 2/20 0.36
▸ TLR2 O60603 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17922808 1.00 GLP1R (0.53) GLP1REPORNOD1CD40CCKAR
SCHEMBL16493176 0.93 GLP1R (0.64) GLP1RNOD1CCKARCCKBR
SCHEMBL17922797 0.92 GLP1R (0.48) GLP1RNOD1CD40TLR2
SCHEMBL17922807 0.91 GLP1R (0.47) GLP1RNOD1CD40TLR2
SCHEMBL17922793 0.90 GLP1R (0.47) GLP1RNOD1CD40CCKARCCKBR
SCHEMBL16493162 0.90 GLP1R (0.47) GLP1RNOD1CD40CCKARCCKBR
SCHEMBL17922789 0.89 GLP1R (0.54) GLP1REPORNOD1CD40TLR2
SCHEMBL16493177 0.86 GLP1R (0.53) GLP1REPORNOD1CD40TLR2
SCHEMBL19049679 0.86 GLP1R (0.52) GLP1REPORNOD1FOLH1
SCHEMBL16382930 0.86 GLP1R (0.58) GLP1REPORNOD1CD40FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160200791-A1 GLP-1 Derivatives, and Uses Thereof NOVO NORDISK A/S (DK) 2016-07-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160200791-A1 GLP-1 Derivatives, and Uses Thereof GLP1R, IAPP, GCG GLP1R 1/4885EPOR 3815/4885NOD1 694/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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