SCHEMBL16493162

SCHEMBL16493162

NC(=O)[C@H](CCCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)[C@@H](N)CCCCNC(=O)CCCCCCCCCCCCCCCS(=O)(=O)O)NI

nearest known ligand 0.47

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.47
▸ CD40 P25942 1/20 0.34
▸ NOD1 Q9Y239 2/20 0.34
▸ TLR2 O60603 2/20 0.34
▸ GNAI3 P08754 1/20 0.34
▸ GNAO1 P09471 1/20 0.34
▸ GNAI1 P63096 1/20 0.34
▸ CCKAR P32238 4/20 0.33
▸ CCKBR P32239 4/20 0.33
▸ ALB P02768 1/20 0.33
▸ DPP7 Q9UHL4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17922793 1.00 GLP1R (0.47) GLP1RCD40NOD1TLR2GNAI3
SCHEMBL17922809 0.93 GLP1R (0.48) GLP1RCD40NOD1TLR2CCKAR
SCHEMBL16493197 0.93 GLP1R (0.48) GLP1RCD40NOD1TLR2CCKAR
SCHEMBL17922798 0.90 GLP1R (0.53) GLP1RCD40NOD1TLR2CCKAR
SCHEMBL17922808 0.90 GLP1R (0.53) GLP1RCD40NOD1TLR2CCKAR
SCHEMBL17922797 0.89 GLP1R (0.48) GLP1RCD40NOD1TLR2GNAI3
SCHEMBL17922807 0.88 GLP1R (0.47) GLP1RCD40NOD1TLR2GNAI3
SCHEMBL16493107 0.88 GLP1R (0.51) GLP1RTLR2CCKARCCKBR
SCHEMBL17922792 0.86 GLP1R (0.46) GLP1RCD40NOD1TLR2GNAI3
SCHEMBL16493127 0.85 GLP1R (0.56) GLP1RNOD1TLR2GNAI3GNAO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160200791-A1 GLP-1 Derivatives, and Uses Thereof NOVO NORDISK A/S (DK) 2016-07-14 — — US disclosed
WO-2015022400-A1 GLP-1 DERIVATIVES, AND USES THEREOF NOVO NORDISK A/S (DK) 2015-02-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160200791-A1 GLP-1 Derivatives, and Uses Thereof GLP1R, IAPP, GCG GLP1R 1/4885CD40 3396/4885NOD1 694/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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