SCHEMBL17922797

SCHEMBL17922797

NC(=O)[C@H](CCCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)[C@@H](N)CCCCNC(=O)[C@@H](N)CCCCNC(=O)CCCCCNC(=O)CCCCCCCCCCCCCCCS)NI

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.48
▸ FNTA P49354 2/20 0.36
▸ FNTB P49356 2/20 0.36
▸ NOD1 Q9Y239 2/20 0.35
▸ CD40 P25942 1/20 0.35
▸ GNAI3 P08754 1/20 0.35
▸ GNAO1 P09471 1/20 0.35
▸ GNAI1 P63096 1/20 0.35
▸ PGGT1B P53609 1/20 0.35
▸ ALB P02768 1/20 0.34
▸ TLR2 O60603 2/20 0.33
▸ DPP7 Q9UHL4 1/20 0.33
▸ ROCK2 O75116 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17922807 0.99 GLP1R (0.47) GLP1RFNTAFNTBNOD1CD40
SCHEMBL17922798 0.92 GLP1R (0.53) GLP1RNOD1CD40TLR2
SCHEMBL17922808 0.92 GLP1R (0.53) GLP1RNOD1CD40TLR2
SCHEMBL16493162 0.89 GLP1R (0.47) GLP1RNOD1CD40GNAI3GNAO1
SCHEMBL17922793 0.89 GLP1R (0.47) GLP1RNOD1CD40GNAI3GNAO1
SCHEMBL16493178 0.86 GLP1R (0.48) GLP1RFNTAFNTBNOD1CD40
SCHEMBL16493061 0.86 GLP1R (0.48) GLP1RFNTAFNTBNOD1CD40
SCHEMBL16493059 0.86 GLP1R (0.48) GLP1RFNTAFNTBNOD1CD40
SCHEMBL17922790 0.85 GLP1R (0.58) GLP1RNOD1GNAI3GNAO1GNAI1
SCHEMBL16493176 0.85 GLP1R (0.64) GLP1RFNTAFNTBNOD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160200791-A1 GLP-1 Derivatives, and Uses Thereof NOVO NORDISK A/S (DK) 2016-07-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160200791-A1 GLP-1 Derivatives, and Uses Thereof GLP1R, IAPP, GCG GLP1R 1/4885FNTA 2094/4885FNTB 2422/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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