Sugi Predict

Sugi Predict / Compounds / SCHEMBL17923664

SCHEMBL17923664

SCHEMBL17923664

c1ccc2/c(c1)=c1/cccc/c1=c1\cc3c4ccccc4c4ccccc4c3c\c1=c1/cccc/c1=2

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ HPRT1 P00492 4/20 0.38
▸ TRPM4 Q8TD43 1/20 0.36
▸ ALDH1A1 P00352 4/20 0.35
▸ HSD17B10 Q99714 4/20 0.35
▸ CYP2A6 P11509 2/20 0.35
▸ TSHR P16473 1/20 0.35
▸ TDP1 Q9NUW8 1/20 0.35
▸ CYP1A2 P05177 3/20 0.35
▸ HIF1A Q16665 1/20 0.35
▸ CYP1B1 Q16678 1/20 0.35
▸ THRB P10828 1/20 0.35
▸ HPGD P15428 1/20 0.35
▸ IDO1 P14902 1/20 0.33
▸ AHR P35869 1/20 0.32
▸ GPR3 P46089 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Triphenylene SCHEMBL28701514 0.86 HPRT1 (0.47) HPRT1TRPM4ALDH1A1HSD17B10CYP2A6
SCHEMBL17923655 0.83 CYP2A6 (0.39) ALDH1A1CYP2A6TDP1AHR
SCHEMBL598133 0.78 HPRT1 (0.47) HPRT1TRPM4ALDH1A1HSD17B10CYP2A6
SCHEMBL7638577 0.78 HPRT1 (0.47) HPRT1TRPM4ALDH1A1HSD17B10CYP2A6
SCHEMBL28569273 0.78 HPRT1 (0.47) HPRT1TRPM4ALDH1A1HSD17B10CYP2A6
SCHEMBL17923610 0.78 MAPT (0.50) ALDH1A1HSD17B10CYP2A6TSHRTDP1
Triphenylene SCHEMBL25597 0.73 HPRT1 (0.57) HPRT1TRPM4ALDH1A1HSD17B10CYP2A6
SCHEMBL49871 0.73 ALOX12 (0.46) ALDH1A1HSD17B10CYP2A6TSHRTDP1
Triphenylene SCHEMBL311118 0.73 HPRT1 (0.57) HPRT1TRPM4ALDH1A1HSD17B10CYP2A6
SCHEMBL31467394 0.73 HPRT1 (0.57) HPRT1TRPM4ALDH1A1HSD17B10CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160211456-A1 PHENANTHRO[9,10-b]TETRAPHENYLENE DERIVATIVE AND USE THEREOF LUMINESCENCE TECHNOLOGY CORP. 2016-07-21 — — US claimed
US-10608185-B2 Organic electroluminescent materials and devices UNIVERAL DISPLAY CORPORATION (US) 2020-03-31 — — US disclosed
US-20180108844-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2018-04-19 — — US disclosed
CN-105801430-A Phenanthro [9,10-b ] tetraphenylene derivative and use thereof 机光科技股份有限公司 2016-07-27 — — CN disclosed
US-20160211456-A1 PHENANTHRO[9,10-b]TETRAPHENYLENE DERIVATIVE AND USE THEREOF LUMINESCENCE TECHNOLOGY CORP. 2016-07-21 — — US disclosed
US-20160211456-A1 PHENANTHRO[9,10-b]TETRAPHENYLENE DERIVATIVE AND USE THEREOF LUMINESCENCE TECHNOLOGY CORP. 2016-07-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180108844-A1 Organic Electroluminescent Materials and Devices SLCO4C1, SLCO2A1, SLCO2B1 HPRT1 391/4885TRPM4 139/4885ALDH1A1 1333/4885
US-10608185-B2 Organic electroluminescent materials and devices SLCO4C1, SLCO2A1, SLCO2B1 HPRT1 391/4885TRPM4 139/4885ALDH1A1 1333/4885
US-20160211456-A1 PHENANTHRO[9,10-b]TETRAPHENYLENE DERIVATIVE AND USE THEREOF POP1, TERB1, AP2B1 HPRT1 587/4885TRPM4 1048/4885ALDH1A1 2052/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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