Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.44 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17925455 | 0.92 | LMNA (0.53) | LMNATP53MEN1KMT2AALDH1A1 | |
| SCHEMBL17935506 | 0.90 | LMNA (0.50) | LMNATP53MEN1KMT2AALDH1A1 | |
| SCHEMBL17925451 | 0.89 | LMNA (0.53) | LMNATP53MEN1KMT2AALDH1A1 | |
| SCHEMBL17925438 | 0.89 | LMNA (0.49) | LMNATP53MEN1KMT2AALDH1A1 | |
| SCHEMBL17925453 | 0.88 | POLB (0.54) | LMNATP53MEN1KMT2AALDH1A1 | |
| SCHEMBL17925436 | 0.88 | LMNA (0.48) | LMNATP53MEN1KMT2AALDH1A1 | |
| SCHEMBL17925432 | 0.88 | RAB9A (0.52) | LMNATP53MEN1KMT2AALDH1A1 | |
| SCHEMBL17925435 | 0.88 | LMNA (0.50) | LMNATP53MEN1KMT2AALDH1A1 | |
| SCHEMBL17925442 | 0.87 | LMNA (0.48) | LMNATP53MEN1KMT2AALDH1A1 | |
| SCHEMBL17925434 | 0.85 | F13A1 (0.51) | LMNATP53MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016112513-A1 | COMPOUNDS AND METHODS FOR INDUCING MESENCHYMAL STEM CELLS INTO CHONDROCYTES | GUANGZHOU INSTITUTES OF BIOMEDICINE AND HEALTH, CHINESE ACADEMY OF SCIENCES (CN) | 2016-07-21 | — | — | WO | claimed |