Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 8/20 | 0.54 |
| ▸ | PCNA | P12004 | 2/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | CDC25B | P30305 | 2/20 | 0.42 |
| ▸ | PTPRB | P23467 | 1/20 | 0.42 |
| ▸ | CDC25A | P30304 | 1/20 | 0.42 |
| ▸ | PTEN | P60484 | 1/20 | 0.42 |
| ▸ | PTPMT1 | Q8WUK0 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1002974 | 0.83 | FFAR1 (0.53) | FFAR1KEAP1CA1CA2CDC25B | |
| SCHEMBL2729682 | 0.81 | HPGD (0.50) | PCNACA2POLBTHRATHRB | |
| SCHEMBL11413993 | 0.80 | FFAR1 (0.50) | FFAR1KEAP1CA1CA2CDC25B | |
| SCHEMBL7781855 | 0.80 | KDM4E (0.57) | FFAR1KEAP1CA1CA2POLB | |
| SCHEMBL30492043 | 0.80 | PCNA (0.66) | FFAR1PCNAKEAP1CA1CA2 | |
| SCHEMBL3269085 | 0.80 | PCNA (0.66) | FFAR1PCNAKEAP1CA1CA2 | |
| SCHEMBL23665797 | 0.79 | CYP3A4 (0.55) | FFAR1KEAP1CA1CA2FFAR4 | |
| SCHEMBL11440235 | 0.79 | ALDH1A1 (0.68) | FFAR1KEAP1CA1CA2POLB | |
| SCHEMBL18830588 | 0.79 | FFAR1 (0.54) | FFAR1PCNAKEAP1POLBTHRA | |
| SCHEMBL11266679 | 0.79 | FFAR1 (0.54) | FFAR1KEAP1CA1CA2CDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016113757-A1 | NOVEL RECYCLABLE IODINATING AGENT AND ITS APPLICATIONS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-07-21 | — | — | WO | disclosed |