Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 12/20 | 0.53 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CDC25B | P30305 | 2/20 | 0.46 |
| ▸ | PTPRB | P23467 | 1/20 | 0.46 |
| ▸ | CDC25A | P30304 | 1/20 | 0.46 |
| ▸ | PTEN | P60484 | 1/20 | 0.46 |
| ▸ | PTPMT1 | Q8WUK0 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | RXRG | P48443 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4700483 | 0.89 | CYP1A2 (0.57) | FFAR1CDC25BALDH1A1CASP6RCE1 | |
| SCHEMBL4512051 | 0.85 | GAA (0.51) | FFAR1KEAP1CA1CA2CDC25B | |
| SCHEMBL7781855 | 0.85 | KDM4E (0.57) | FFAR1KEAP1CA1CA2CDC25B | |
| SCHEMBL11413993 | 0.85 | FFAR1 (0.50) | FFAR1KEAP1CA1CA2CDC25B | |
| SCHEMBL23665797 | 0.83 | CYP3A4 (0.55) | FFAR1KEAP1CA1CA2FFAR4 | |
| SCHEMBL8827540 | 0.83 | ALDH1A1 (0.49) | FFAR1KEAP1CA1CA2CDC25B | |
| SCHEMBL11266679 | 0.83 | FFAR1 (0.54) | FFAR1KEAP1CA1CA2CDC25B | |
| SCHEMBL1931989 | 0.83 | FFAR1 (0.50) | FFAR1KEAP1CA1CA2CDC25B | |
| SCHEMBL17926089 | 0.83 | FFAR1 (0.54) | FFAR1KEAP1CA1CA2CDC25B | |
| SCHEMBL7282363 | 0.83 | SKP2 (0.56) | FFAR1KEAP1CA1CA2FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10703727-B2 | Method for preparing substituted 3-(2-anilino-1-cyclohexyl-1H-benzimidazol-5-yl)propanoic acid derivatives | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2020-07-07 | — | — | US | disclosed |
| US-20180222871-A1 | METHOD FOR PREPARING SUBSTITUTED 3-(2-ANILINO-1-CYCLOHEXYL-1H-BENZIMIDAZOL-5-YL)PROPANOIC ACID DERIVATIVES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-08-09 | — | — | US | disclosed |
| US-7868135-B2 | Compositions of lipopeptide antibiotic derivatives and methods of use thereof | BIOWEST THERAPEUTICS INC. (CA) | 2011-01-11 | — | — | US | disclosed |
| EP-2147925-A1 | Compositions of lipopeptide antibiotic derivatives and methods of use thereof | MIGENIX INC. (CA) | 2010-01-27 | — | — | EP | disclosed |
| US-20080171783-A1 | COMPOSITIONS AND METHODS FOR TREATING HYPERPROLIFERATIVE DISEASE | MIGENIX INC. (CA) | 2008-07-17 | — | — | US | disclosed |
| EP-1910279-A2 | NON-NUCLEOSIDE ANTI-HEPACIVIRUS AGENTS AND USES THEREOF | MIGENIX INC. (CA) | 2008-04-16 | — | — | EP | disclosed |
| US-20070021434-A1 | NON-NUCLEOSIDE ANTI-HEPACIVIRUS AGENTS AND USES THEREOF | MIGENIX INC. (CA) | 2007-01-25 | — | — | US | disclosed |
| WO-2007002639-A2 | NON-NUCLEOSIDE ANTI-HEPACIVIRUS AGENTS AND USES THEREOF | MIGENIX INC. (CA) | 2007-01-04 | — | — | WO | disclosed |
| US-20050153876-A1 | Compositions of lipopeptide antibiotic derivatives and methods of use thereof | MIGENIX INC. (CA) | 2005-07-14 | — | — | US | disclosed |
| EP-0250676-B1 | NON-ENZYMATIC IMMUNOHISTOCHEMICAL STAINING SYSTEM AND REAGENTS | Immunomedics, Inc. (US) | 1993-03-10 | — | — | EP | disclosed |
| US-4792521-A | Non-enzymatic immunohistochemical staining system and reagents | IMMUNOMEDICS, INC. (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0250676-A2 | Non-enzymatic immunohistochemical staining system and reagents | Immunomedics, Inc. (US) | 1988-01-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021434-A1 | NON-NUCLEOSIDE ANTI-HEPACIVIRUS AGENTS AND USES THEREOF | HAVCR2, ADAR, NSUN2 | FFAR1 887/4885KEAP1 2576/4885CA1 4464/4885 |
| US-10703727-B2 | Method for preparing substituted 3-(2-anilino-1-cyclohexyl-1H-benzimidazol-5-yl)propanoic acid derivatives | HCAR3, AKR1C3, HCAR2 | FFAR1 9/4885KEAP1 1874/4885CA1 514/4885 |
| US-20050153876-A1 | Compositions of lipopeptide antibiotic derivatives and methods of use thereof | NRDC, NOD2, NGLY1 | FFAR1 2626/4885KEAP1 2843/4885CA1 4778/4885 |
| US-20180222871-A1 | METHOD FOR PREPARING SUBSTITUTED 3-(2-ANILINO-1-CYCLOHEXYL-1H-BENZIMIDAZOL-5-YL)PROPANOIC ACID DERIVATIVES | HCAR3, AKR1C3, HCAR2 | FFAR1 9/4885KEAP1 1874/4885CA1 514/4885 |
| US-20080171783-A1 | COMPOSITIONS AND METHODS FOR TREATING HYPERPROLIFERATIVE DISEASE | POLQ, POLI, POLH | FFAR1 4076/4885KEAP1 3833/4885CA1 4583/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.