Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | THRB | P10828 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RARB | P10826 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | ACACA | Q13085 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9271331 | 0.86 | MAPT (0.49) | MAPTTHRBSMN1; SMN2RAB9ATP53 | |
| SCHEMBL5669096 | 0.86 | THRB (0.53) | MAPTTHRBSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL17931043 | 0.85 | ELANE (0.51) | MAPTSMN1; SMN2RAB9ANPC1HSD17B10 | |
| SCHEMBL10306589 | 0.84 | MAPT (0.60) | MAPTTHRBSMN1; SMN2RAB9ATP53 | |
| SCHEMBL9817392 | 0.78 | MAPT (0.67) | MAPTTHRBSMN1; SMN2RAB9ATP53 | |
| SCHEMBL9266037 | 0.78 | MAPT (0.54) | MAPTTHRBSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL3899589 | 0.77 | THRB (0.66) | MAPTTHRBSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL9265474 | 0.77 | MAPT (0.56) | MAPTTHRBSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL11307746 | 0.76 | MAPT (0.67) | MAPTTHRBSMN1; SMN2RAB9ATP53 | |
| SCHEMBL11785681 | 0.76 | THRB (0.64) | MAPTTHRBSMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160209561-A1 | Photochromic Articles That Include Photochromic-Dichroic Materials | TRANSITIONS OPTICAL, INC. | 2016-07-21 | — | — | US | disclosed |