Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 6/20 | 0.64 |
| ▸ | AXL | P30530 | 3/20 | 0.55 |
| ▸ | FLT3 | P36888 | 3/20 | 0.55 |
| ▸ | MERTK | Q12866 | 3/20 | 0.55 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.54 |
| ▸ | FLT1 | P17948 | 1/20 | 0.49 |
| ▸ | CDK8 | P49336 | 1/20 | 0.49 |
| ▸ | CDK9 | P50750 | 1/20 | 0.49 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.49 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15730182 | 0.83 | TGFBR1 (0.64) | TGFBR1AXLFLT3MERTKDYRK1A | |
| SCHEMBL26175287 | 0.81 | KIT (0.58) | TGFBR1AXLFLT3MERTKCDK8 | |
| SCHEMBL17934721 | 0.80 | TGFBR1 (0.56) | TGFBR1AXLFLT3MERTKDYRK1A | |
| SCHEMBL21084225 | 0.79 | TGFBR1 (1.00) | TGFBR1TGFBR2 | |
| SCHEMBL1576521 | 0.78 | DYRK1A (0.73) | TGFBR1AXLFLT3MERTKDYRK1A | |
| SCHEMBL31040013 | 0.77 | DYRK1A (0.58) | TGFBR1AXLFLT3MERTKDYRK1A | |
| SCHEMBL15723967 | 0.77 | TGFBR1 (0.57) | TGFBR1AXLFLT3MERTKDYRK1A | |
| SCHEMBL14826052 | 0.77 | DYRK1A (0.85) | TGFBR1AXLFLT3MERTKDYRK1A | |
| SCHEMBL30639468 | 0.76 | DYRK1A (0.55) | TGFBR1AXLFLT3MERTKDYRK1A | |
| SCHEMBL15639573 | 0.76 | TGFBR1 (0.56) | TGFBR1AXLFLT3MERTKDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170282170-A9 | PHOSPHORUS-CONTAINING CATALYSTS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2017-10-05 | — | — | US | disclosed |
| US-20160207034-A1 | PHOSPHORUS-CONTAINING CATALYSTS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2016-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160207034-A1 | PHOSPHORUS-CONTAINING CATALYSTS | AR, NR2C2, ORC3 | TGFBR1 659/4885AXL 2322/4885FLT3 2917/4885 |
| US-20170282170-A9 | PHOSPHORUS-CONTAINING CATALYSTS | AR, NR2C2, ORC3 | TGFBR1 659/4885AXL 2322/4885FLT3 2917/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.