Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.55 |
| ▸ | GRM5 | P41594 | 13/20 | 0.52 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
| ▸ | CDK9 | P50750 | 1/20 | 0.41 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | AXL | P30530 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | MERTK | Q12866 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26175289 | 0.83 | KIT (0.56) | CDK8CDK9AXL | |
| SCHEMBL360651 | 0.78 | DYRK1A (0.74) | DYRK1AGRM5CDK8ROCK1CLK4 | |
| SCHEMBL15640104 | 0.77 | DYRK1A (0.54) | DYRK1AGRM5TGFBR1KDM4EMEN1 | |
| SCHEMBL30639464 | 0.77 | GRM5 (0.54) | DYRK1AGRM5TGFBR1KDM4EALDH1A1 | |
| SCHEMBL18623821 | 0.76 | ALDH1A1 (0.46) | DYRK1AGRM5TGFBR1KDM4EALDH1A1 | |
| SCHEMBL17930295 | 0.76 | TGFBR1 (0.64) | DYRK1AFLT1CDK8CDK9LIMK1 | |
| SCHEMBL23587109 | 0.76 | GRM5 (0.53) | DYRK1AGRM5GRIN2B | |
| SCHEMBL15639956 | 0.76 | DYRK1A (0.43) | DYRK1AGRM5TGFBR1GRIN2B | |
| SCHEMBL15637963 | 0.76 | TGFBR1 (0.46) | DYRK1AGRM5TGFBR1KDM4EMEN1 | |
| SCHEMBL20190138 | 0.74 | SCN5A (0.47) | DYRK1AGRM5KDM4ENPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3842436-B1 | PHARMACEUTICAL COMPOSITIONS COMPRISING IMIDAZOPYRIMIDINE OR IMIDAZOTRIAZINE DERIVATIVES FOR USE IN THE TREATMENT OF SCHIZOPHRENIA | SK BIOPHARMACEUTICALS CO LTD (KR) | 2023-11-08 | — | — | EP | claimed |