Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 19/20 | 0.76 |
| ▸ | MAOA | P21397 | 3/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16552377 | 0.86 | MAOB (1.00) | MAOBMAOANR4A2 | |
| SCHEMBL17931617 | 0.86 | MAOB (0.74) | MAOBMAOA | |
| SCHEMBL17931615 | 0.80 | MAOB (0.55) | MAOBMAOA | |
| SCHEMBL17931584 | 0.80 | MAOB (0.73) | MAOBMAOANR4A2 | |
| SCHEMBL17923817 | 0.79 | MAOB (0.52) | MAOBMAOANR4A2 | |
| SCHEMBL16552343 | 0.79 | MAOB (0.48) | MAOBMAOA | |
| SCHEMBL8925517 | 0.74 | PTPN1 (0.66) | MAOB | |
| SCHEMBL16552376 | 0.74 | MAOB (1.00) | MAOBMAOA | |
| Hydrochloric Acid SCHEMBL17923795 | 0.73 | MAOB (0.98) | MAOBMAOA | |
| Hydrochloric Acid SCHEMBL17923792 | 0.73 | MAOB (0.98) | MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160207878-A1 | MAO-B Selective Inhibitor Compounds, Pharmaceutical Compositions Thereof and Uses Thereof | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2016-07-21 | — | — | US | disclosed |
| US-20160207878-A1 | MAO-B Selective Inhibitor Compounds, Pharmaceutical Compositions Thereof and Uses Thereof | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2016-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160207878-A1 | MAO-B Selective Inhibitor Compounds, Pharmaceutical Compositions Thereof and Uses Thereof | MAOB, MAOA, COMT | MAOB 1/4885MAOA 2/4885NR4A2 3011/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.