Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.66 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.60 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.60 |
| ▸ | BCL2 | P10415 | 3/20 | 0.55 |
| ▸ | ACE | P12821 | 1/20 | 0.55 |
| ▸ | ITGA4 | P13612 | 4/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
| ▸ | KDM4A | O75164 | 1/20 | 0.51 |
| ▸ | YAP1 | P46937 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6129676 | 0.92 | PTPN1 (0.61) | PTPN1ITGB3ITGA2BBCL2ACE | |
| SCHEMBL6129624 | 0.92 | PTPN1 (0.61) | PTPN1ITGB3ITGA2BBCL2ACE | |
| SCHEMBL1309887 | 0.88 | ITGA4 (0.62) | PTPN1ITGB3ITGA2BITGA4 | |
| SCHEMBL4417313 | 0.88 | ITGA4 (0.62) | PTPN1ITGB3ITGA2BITGA4 | |
| SCHEMBL838170 | 0.88 | ITGA4 (0.62) | PTPN1ITGB3ITGA2BITGA4 | |
| SCHEMBL29398157 | 0.88 | PTPN1 (0.54) | PTPN1ITGB3ITGA2BBCL2ACE | |
| SCHEMBL193474 | 0.87 | PTPN1 (0.73) | PTPN1ITGB3ITGA2BBCL2ACE | |
| SCHEMBL2891538 | 0.87 | PTPN1 (0.73) | PTPN1ITGB3ITGA2BBCL2ACE | |
| SCHEMBL193473 | 0.87 | PTPN1 (0.73) | PTPN1ITGB3ITGA2BBCL2ACE | |
| SCHEMBL28267499 | 0.85 | PTPN1 (0.77) | PTPN1ITGB3ITGA2BBCL2ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5700905-A | HEXAPEPTIDES, CYCLIC PEPTIDES; AS BINDING G-PROTEIN-LINKED RECEPTORS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1997-12-23 | — | — | US | disclosed |