Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 11/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.51 |
| ▸ | MYC | P01106 | 8/20 | 0.49 |
| ▸ | IDO1 | P14902 | 4/20 | 0.49 |
| ▸ | MAX | P61244 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3506039 | 0.79 | MEN1 (0.64) | MEN1KMT2AMYCIDO1MAX | |
| SCHEMBL30520963 | 0.75 | MEN1 (0.57) | MEN1KMT2AMYCIDO1MAX | |
| SCHEMBL12337785 | 0.74 | IDO1 (0.60) | MEN1KMT2AMYCIDO1MAX | |
| SCHEMBL31071735 | 0.73 | IDO1 (0.46) | MEN1KMT2AMYCIDO1MAX | |
| SCHEMBL21783942 | 0.73 | GSTM2 (0.56) | MEN1KMT2AMYCIDO1MAX | |
| SCHEMBL18894373 | 0.73 | GSTM2 (0.50) | MEN1KMT2AMYCIDO1MAX | |
| SCHEMBL612306 | 0.72 | IDO1 (0.65) | MEN1KMT2AMYCIDO1MAX | |
| SCHEMBL9099360 | 0.72 | MEN1 (0.64) | MEN1KMT2AMYCIDO1MAX | |
| SCHEMBL1071570 | 0.72 | MYC (0.55) | MEN1KMT2AMYCIDO1MAX | |
| SCHEMBL8790979 | 0.71 | MEN1 (0.55) | MEN1KMT2AMYCIDO1MAX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180011100-A1 | METHODS OF SELECTING AND ISOLATING CANCER STEM CELLS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-01-11 | — | — | US | claimed |
| WO-2016073737-A1 | METHODS OF SELECTING AND ISOLATING CANCER STEM CELLS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-05-12 | — | — | WO | claimed |
| US-20180011100-A1 | METHODS OF SELECTING AND ISOLATING CANCER STEM CELLS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-01-11 | — | — | US | disclosed |
| WO-2016073737-A1 | METHODS OF SELECTING AND ISOLATING CANCER STEM CELLS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-05-12 | — | — | WO | disclosed |
| US-7943586-B2 | Antineoplastic agents targeted via glut transporters | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2011-05-17 | — | — | US | disclosed |
| US-20080269112-A1 | Antineoplastic Agents Targeted via Glut Transporters | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2008-10-30 | — | — | US | disclosed |
| US-20060171893-A1 | Antineoplastic agents targeted via glut transporters | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2006-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060171893-A1 | Antineoplastic agents targeted via glut transporters | SLC2A1, SLC2A2, SLC2A4 | MEN1 3856/4885KMT2A 1041/4885MYC 147/4885 |
| US-20080269112-A1 | Antineoplastic Agents Targeted via Glut Transporters | SLC2A1, SLC2A2, SLC2A4 | MEN1 3253/4885KMT2A 1941/4885MYC 326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.