Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 11/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.64 |
| ▸ | MYC | P01106 | 7/20 | 0.64 |
| ▸ | IDO1 | P14902 | 4/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | MAX | P61244 | 3/20 | 0.60 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | MIF | P14174 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8788690 | 0.85 | MEN1 (0.66) | MEN1KMT2AMYCIDO1POLB | |
| SCHEMBL7052057 | 0.84 | GSTM2 (0.66) | MEN1KMT2AMYCIDO1POLB | |
| SCHEMBL27934659 | 0.83 | MEN1 (0.64) | MEN1KMT2AMYCIDO1POLB | |
| SCHEMBL612306 | 0.83 | IDO1 (0.65) | MEN1KMT2AMYCIDO1POLB | |
| SCHEMBL593192 | 0.83 | MEN1 (0.64) | MEN1KMT2AMYCIDO1POLB | |
| SCHEMBL7904806 | 0.83 | MEN1 (0.64) | MEN1KMT2AMYCIDO1POLB | |
| Hydrazine SCHEMBL28939827 | 0.82 | MEN1 (0.62) | MEN1KMT2AMYCIDO1POLB | |
| SCHEMBL3506039 | 0.81 | MEN1 (0.64) | MEN1KMT2AMYCIDO1POLB | |
| SCHEMBL14266890 | 0.81 | MEN1 (0.61) | MEN1KMT2AMYCIDO1POLB | |
| SCHEMBL8427049 | 0.80 | GSTM2 (0.81) | MEN1KMT2AMYCIDO1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993003382-A2 | CHARACTERIZATION OF SPECIFIC DRUG RECEPTORS WITH FLUORESCENT LIGANDS | PHARMACEUTICAL DISCOVERY CORPORATION (US) | 1993-02-18 | — | — | WO | claimed |
| US-5576436-A | FLUORESCENT LABELED LIGANDS FOR MEASUREMENT OF RECEPTORS | PHARMACEUTICAL DISCOVERY CORPORATION (US) | 1996-11-19 | — | — | US | disclosed |