Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | PTPRC | P08575 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TPH1 | P17752 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | ALPI | P09923 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | XIAP | P98170 | 1/20 | 0.30 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16561804 | 0.87 | CYP1A2 (0.44) | PTPRCHSD17B10TPH1PTPN1CYP1A2 | |
| SCHEMBL17933370 | 0.83 | FDPS (0.38) | FDPSESR1ESR2 | |
| SCHEMBL16561817 | 0.83 | FDPS (0.40) | FDPSESR1ESR2CYP1A2 | |
| SCHEMBL17933339 | 0.80 | PTPRC (0.31) | PTPRCHSD17B10PTPN1SLC7A5 | |
| SCHEMBL17933365 | 0.78 | FDPS (0.38) | FDPSPTPRCHSD17B10CYP1A2 | |
| SCHEMBL17933345 | 0.78 | FDPS (0.38) | FDPSPTPRCHSD17B10CYP1A2 | |
| SCHEMBL17656768 | 0.78 | PTPRC (0.46) | PTPRCESR1ESR2HSD17B10TPH1 | |
| SCHEMBL17933342 | 0.78 | PTPRC (0.30) | PTPRC | |
| SCHEMBL17933353 | 0.75 | CYP1A2 (0.36) | HSD17B10CYP1A2 | |
| SCHEMBL16131656 | 0.73 | PTPRA (0.56) | FDPSTPH1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160207948-A1 | PHOSPHOHISTIDINE AND PHOSPHOTYROSINE ANALOGUES | UNIVERSITY OF SHEFFIELD (GB) | 2016-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160207948-A1 | PHOSPHOHISTIDINE AND PHOSPHOTYROSINE ANALOGUES | HRH3, CYTH3, CYTH2 | FDPS 3192/4885PTPRC 75/4885ESR1 2908/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.