Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.53 |
| ▸ | MGAM | O43451 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.51 |
| ▸ | CISD1 | Q9NZ45 | 4/20 | 0.51 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.51 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.51 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.51 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.51 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.51 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4215334 | 0.91 | KDM4E (0.55) | PIM1MGAMCA12CA1CA2 | |
| SCHEMBL4828044 | 0.91 | KDM4E (0.55) | PIM1MGAMCA12CA1CA2 | |
| SCHEMBL7464201 | 0.83 | CISD1 (0.71) | MGAMCA12CA1CA2CA9 | |
| SCHEMBL8388794 | 0.83 | CISD1 (0.71) | MGAMCA12CA1CA2CA9 | |
| SCHEMBL11321794 | 0.83 | CISD1 (0.71) | MGAMCA12CA1CA2CA9 | |
| SCHEMBL12177140 | 0.81 | CYP1A2 (0.53) | PIM1PIM2CISD1MAOBKMT2A | |
| SCHEMBL17934519 | 0.81 | MYC (0.63) | PIM1PIM2CISD1MAOBKMT2A | |
| SCHEMBL12177689 | 0.81 | AKR1B1 (0.60) | CISD1MAOBMAOATDP1NPC1 | |
| SCHEMBL17934622 | 0.80 | ALDH1A1 (0.60) | PIM1PIM2THRBKMT2AMEN1 | |
| SCHEMBL4834121 | 0.78 | AKR1B1 (0.61) | CISD1MAOBKMT2AMEN1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016115360-A1 | C-MYC LIGANDS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME | COFERON, INC. (US) | 2016-07-21 | — | — | WO | disclosed |