Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PTPRC | P08575 | 1/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17933341 | 0.87 | — | — | |
| SCHEMBL17936286 | 0.77 | CYP1A2 (0.42) | CYP3A4SLC7A5CYP1A2HSD17B10PTPRC | |
| SCHEMBL17936284 | 0.75 | HSD17B10 (0.41) | CYP3A4SLC7A5CYP1A2HSD17B10PTPRC | |
| SCHEMBL20379773 | 0.70 | MMP1 (0.33) | — | |
| SCHEMBL16561804 | 0.70 | CYP1A2 (0.44) | CYP3A4SLC7A5CYP1A2HSD17B10PTPRC | |
| SCHEMBL17936302 | 0.70 | SLC7A5 (0.39) | CYP3A4SLC7A5CYP1A2HSD17B10PTPRC | |
| SCHEMBL17936294 | 0.70 | SLC7A5 (0.39) | CYP3A4SLC7A5CYP1A2HSD17B10PTPRC | |
| SCHEMBL17936281 | 0.70 | SLC7A5 (0.45) | CYP3A4SLC7A5HSD17B10PTPRC | |
| SCHEMBL1768807 | 0.69 | CYP1A2 (0.50) | CYP3A4SLC7A5CYP1A2HSD17B10SLC1A3 | |
| SCHEMBL1768809 | 0.69 | CYP1A2 (0.50) | CYP3A4SLC7A5CYP1A2HSD17B10SLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160207948-A1 | PHOSPHOHISTIDINE AND PHOSPHOTYROSINE ANALOGUES | UNIVERSITY OF SHEFFIELD (GB) | 2016-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160207948-A1 | PHOSPHOHISTIDINE AND PHOSPHOTYROSINE ANALOGUES | HRH3, CYTH3, CYTH2 | CYP3A4 3710/4885SLC7A5 2977/4885CYP1A2 4128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.