SCHEMBL17940725

SCHEMBL17940725

N#Cc1cc2ncn(-c3ccccc3)c2cc1C#N

nearest known ligand 0.59

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ FGFR1 P11362 10/20 0.59
▸ SRC P12931 3/20 0.59
▸ HTT P42858 2/20 0.54
▸ ALDH1A1 P00352 1/20 0.50
▸ HPGD P15428 1/20 0.50
▸ MAPK1 P28482 1/20 0.50
▸ MAPK10 P53779 1/20 0.50
▸ NCOA1 Q15788 1/20 0.50
▸ NCOA3 Q9Y6Q9 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24844327 0.84 FGFR1 (0.50) FGFR1SRCHTTALDH1A1HPGD
SCHEMBL17940768 0.84 HPGD (0.53) FGFR1ALDH1A1HPGD
SCHEMBL23846263 0.82 FGFR1 (0.76) FGFR1SRCHTTALDH1A1HPGD
SCHEMBL8009170 0.79 FGFR1 (0.60) FGFR1SRCHTTALDH1A1
SCHEMBL17940687 0.79 HTT (0.57) FGFR1SRCHTTALDH1A1HPGD
SCHEMBL17940706 0.75 HTT (0.51) FGFR1SRCHTT
SCHEMBL17940717 0.75 FGFR1 (0.61) FGFR1SRCHTTALDH1A1
SCHEMBL7993203 0.75 FGFR1 (1.00) FGFR1SRCHTT
SCHEMBL11678470 0.75 FGFR1 (0.65) FGFR1SRCHTTALDH1A1HPGD
SCHEMBL31294911 0.75 FGFR1 (0.65) FGFR1SRCHTTALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114933614-A Organic electroluminescent material and device 环球展览公司 2022-08-23 — — CN disclosed
CN-105820122-B Organic electroluminescent material and device 环球展览公司 2022-05-17 — — CN disclosed
US-10418569-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-09-17 — — US disclosed
US-10418569-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-09-17 — — US disclosed
US-20160218303-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-07-28 — — US disclosed
US-20160218303-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-07-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10418569-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, OSBP2 FGFR1 2889/4885SRC 1034/4885HTT 2766/4885
US-20160218303-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OSBP2 FGFR1 2889/4885SRC 1034/4885HTT 2766/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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