SCHEMBL24844327

SCHEMBL24844327

N#Cc1cc2c(cc1C(F)(F)F)ncn2-c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ FGFR1 P11362 9/20 0.50
▸ SRC P12931 3/20 0.50
▸ HTT P42858 2/20 0.45
▸ CHRNB2 P17787 1/20 0.44
▸ CHRNA4 P43681 1/20 0.44
▸ ALDH1A1 P00352 1/20 0.43
▸ HPGD P15428 1/20 0.43
▸ MAPK1 P28482 1/20 0.43
▸ MAPK10 P53779 1/20 0.43
▸ NCOA1 Q15788 1/20 0.43
▸ NCOA3 Q9Y6Q9 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17940725 0.84 FGFR1 (0.59) FGFR1SRCHTTALDH1A1HPGD
SCHEMBL24844368 0.75 FGFR1 (0.40) FGFR1SRCHTTALDH1A1
SCHEMBL23846263 0.74 FGFR1 (0.76) FGFR1SRCHTTALDH1A1HPGD
SCHEMBL19848423 0.73 HTT (0.59) FGFR1SRCHTTALDH1A1HPGD
SCHEMBL19915930 0.73 FGFR1 (0.62) FGFR1SRCHTTALDH1A1
SCHEMBL8009170 0.72 FGFR1 (0.60) FGFR1SRCHTTALDH1A1
SCHEMBL17940687 0.72 HTT (0.57) FGFR1SRCHTTALDH1A1HPGD
SCHEMBL1761803 0.71 GABRA1 (0.78) FGFR1ALDH1A1HPGD
SCHEMBL11678470 0.70 FGFR1 (0.65) FGFR1SRCHTTALDH1A1HPGD
SCHEMBL17940768 0.70 HPGD (0.53) FGFR1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230006152-A1 METAL COMPLEX AND LIGHT EMITTING DEVICE CITY UNIVERSITY OF HONG KONG (HK) 2023-01-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230006152-A1 METAL COMPLEX AND LIGHT EMITTING DEVICE OCIAD1, OCIAD2, OPRD1 FGFR1 4472/4885SRC 3518/4885HTT 2976/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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