SCHEMBL17945656

SCHEMBL17945656

c1ccc2c(c1)oc1cc3oc4ccc(-c5c6ccccc6c(-c6ccc7sc8ccccc8c7c6)c6ccccc56)cc4c3cc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.41
ALDH1A1 P00352 3/20 0.41
HPGD P15428 3/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
AHR P35869 2/20 0.41
NPC1 O15118 2/20 0.41
KDM4E B2RXH2 2/20 0.41
RAB9A P51151 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
MAOA P21397 1/20 0.40
GPR3 P46089 1/20 0.39
CYP1A2 P05177 3/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C19 P33261 1/20 0.35
HSP90AA1 P07900 1/20 0.34
HSP90AB1 P08238 1/20 0.34
PLA2G2A P14555 1/20 0.33
PLA2G4A P47712 1/20 0.33
CHEK2 O96017 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21388985 0.96 MAPT (0.44) MAPTALDH1A1HPGDMEN1KMT2A
SCHEMBL17945551 0.94 MAPT (0.41) MAPTALDH1A1HPGDMEN1KMT2A
SCHEMBL23428097 0.93 GPR3 (0.40) MAPTALDH1A1HPGDMEN1KMT2A
SCHEMBL21450731 0.93 GPR3 (0.45) MAPTALDH1A1HPGDMEN1KMT2A
SCHEMBL15195408 0.90 PLA2G2A (0.42) MAPTALDH1A1HPGDMEN1KMT2A
SCHEMBL23426917 0.90 MAPT (0.41) MAPTALDH1A1HPGDMEN1KMT2A
SCHEMBL23427200 0.89 GPR3 (0.37) MAPTALDH1A1HPGDMEN1KMT2A
SCHEMBL23428217 0.89 GPR3 (0.37) MAPTALDH1A1HPGDMEN1KMT2A
SCHEMBL17944180 0.89 MAPT (0.41) MAPTALDH1A1HPGDMEN1KMT2A
SCHEMBL17944543 0.89 MAPT (0.41) MAPTALDH1A1HPGDMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160218297-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-07-28 US disclosed
US-20160218297-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-07-28 US disclosed