Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.84 |
| ▸ | ADIPOR2 | Q86V24 | 1/20 | 0.78 |
| ▸ | ADIPOR1 | Q96A54 | 1/20 | 0.78 |
| ▸ | USP2 | O75604 | 1/20 | 0.74 |
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.73 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.66 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17946047 | 0.90 | POLB (0.91) | POLBADIPOR2ADIPOR1USP2SIGMAR1 | |
| SCHEMBL24514563 | 0.90 | POLB (0.86) | POLBADIPOR2ADIPOR1USP2SIGMAR1 | |
| SCHEMBL17938602 | 0.88 | ADIPOR2 (1.00) | POLBADIPOR2ADIPOR1USP2SIGMAR1 | |
| SCHEMBL24514564 | 0.87 | ADIPOR2 (0.82) | POLBADIPOR2ADIPOR1USP2SIGMAR1 | |
| SCHEMBL17950883 | 0.85 | ADIPOR2 (0.90) | POLBADIPOR2ADIPOR1USP2SIGMAR1 | |
| SCHEMBL8035540 | 0.84 | SIGMAR1 (1.00) | SIGMAR1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5129236 | 0.83 | MCHR1 (0.83) | POLBADIPOR2ADIPOR1USP2SIGMAR1 | |
| SCHEMBL17946000 | 0.83 | POLB (0.74) | POLBADIPOR2ADIPOR1USP2SIGMAR1 | |
| SCHEMBL24514573 | 0.83 | POLB (0.74) | POLBADIPOR2ADIPOR1USP2SIGMAR1 | |
| SCHEMBL25568935 | 0.83 | POLB (0.74) | POLBADIPOR2ADIPOR1USP2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170298051-A1 | ACTIVATOR OF ADIPONECTIN RECEPTOR | THE UNIVERSITY OF TOKYO (JP) | 2017-10-19 | — | — | US | disclosed |
| US-20170298051-A1 | ACTIVATOR OF ADIPONECTIN RECEPTOR | THE UNIVERSITY OF TOKYO (JP) | 2017-10-19 | — | — | US | disclosed |
| EP-3053911-A1 | ADIPONECTIN RECEPTOR-ACTIVATING COMPOUND | The University of Tokyo (JP) | 2016-08-10 | — | — | EP | disclosed |
| US-20160214967-A1 | ACTIVATOR OF ADIPONECTIN RECEPTOR | THE UNIVERSITY OF TOKYO (JP) | 2016-07-28 | — | — | US | disclosed |
| US-20160214967-A1 | ACTIVATOR OF ADIPONECTIN RECEPTOR | THE UNIVERSITY OF TOKYO (JP) | 2016-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160214967-A1 | ACTIVATOR OF ADIPONECTIN RECEPTOR | ADIPOR1, ADIPOR2, CCKAR | POLB 4574/4885ADIPOR2 2/4885ADIPOR1 1/4885 |
| US-20170298051-A1 | ACTIVATOR OF ADIPONECTIN RECEPTOR | ADIPOR1, ADIPOR2, CCKAR | POLB 4574/4885ADIPOR2 2/4885ADIPOR1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.