Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | GLA | P06280 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27140779 | 0.79 | KDM4E (0.48) | KDM4EALDH1A1HPGDKMT2ALCK | |
| SCHEMBL27140781 | 0.79 | KDM4E (0.48) | KDM4EALDH1A1HPGDKMT2ALCK | |
| SCHEMBL4211629 | 0.73 | CYP3A4 (0.61) | — | |
| SCHEMBL4208391 | 0.73 | MAOB (0.72) | CYP2D6 | |
| SCHEMBL20767986 | 0.73 | KDM4E (0.56) | KDM4EALDH1A1HPGDCYP2D6KMT2A | |
| SCHEMBL20780149 | 0.71 | KDM4E (0.53) | KDM4EALDH1A1HPGDCYP2D6KMT2A | |
| SCHEMBL14473750 | 0.70 | KDM4E (0.76) | KDM4EALDH1A1HPGDCYP2D6LCK | |
| SCHEMBL8863327 | 0.70 | KDM4E (0.65) | KDM4EALDH1A1HPGDCYP2D6KMT2A | |
| SCHEMBL716585 | 0.70 | KDM4E (0.52) | KDM4EALDH1A1HPGDCYP2D6LCK | |
| SCHEMBL26195520 | 0.68 | CYP2D6 (0.62) | KDM4EALDH1A1HPGDCYP2D6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016118305-A1 | COUMARIN-BASED COMPOUNDS AND RELATED METHODS | BIOSEARCH TECHNOLOGIES, INC. (US) | 2016-07-28 | — | — | WO | disclosed |