Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.48 |
| ▸ | GAA | P10253 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | GLA | P06280 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27140781 | 1.00 | KDM4E (0.48) | KDM4EGAAALDH1A1GLAMAPT | |
| SCHEMBL5622971 | 0.81 | MEN1 (0.60) | KDM4EGAAALDH1A1GLAMAPT | |
| SCHEMBL17948536 | 0.79 | KDM4E (0.47) | KDM4EGAAALDH1A1GLAMAPT | |
| SCHEMBL20767986 | 0.73 | KDM4E (0.56) | KDM4EGAAALDH1A1GLAMAPT | |
| SCHEMBL1305584 | 0.71 | KDM4E (0.49) | KDM4EGAAALDH1A1GLAMAPT | |
| SCHEMBL16715181 | 0.70 | KDM4E (0.49) | KDM4EGAAALDH1A1GLAMAPT | |
| SCHEMBL16715180 | 0.70 | KDM4E (0.49) | KDM4EGAAALDH1A1GLAMAPT | |
| SCHEMBL8717972 | 0.70 | SCN9A (0.49) | SCN9A | |
| SCHEMBL8717966 | 0.70 | SCN9A (0.49) | SCN9A | |
| SCHEMBL1087185 | 0.70 | ITGB3 (0.65) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260062447-A1 | COMPOUNDS | UNIV SOUTHAMPTON (GB) | 2026-03-05 | — | — | US | disclosed |
| WO-2024042313-A1 | COMPOUNDS | UNIVERSITY OF SOUTHAMPTON (GB) | 2024-02-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260062447-A1 | COMPOUNDS | VHL, HIF1A, HYOU1 | KDM4E 349/4885GAA 4675/4885ALDH1A1 1654/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.