Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMO | O15229 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17950590 | 0.83 | SMN1; SMN2 (0.44) | GPR139NPC1SMN1; SMN2RAB9AKMT2A | |
| SCHEMBL28488673 | 0.80 | GPR139 (0.42) | GPR139KMT2AALDH1A1MEN1 | |
| SCHEMBL5816179 | 0.80 | KMT2A (0.68) | NPC1SMN1; SMN2MAPTRAB9AKMT2A | |
| SCHEMBL17950528 | 0.80 | NPC1 (0.43) | GPR139NPC1SMN1; SMN2RAB9AKMT2A | |
| SCHEMBL17950516 | 0.79 | TDP1 (0.45) | SMN1; SMN2MAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL17766913 | 0.77 | GPR139 (0.60) | GPR139NPC1SMN1; SMN2MAPTRAB9A | |
| SCHEMBL30557834 | 0.77 | GPR139 (0.60) | GPR139NPC1SMN1; SMN2MAPTRAB9A | |
| SCHEMBL17950503 | 0.76 | KMT2A (0.40) | KMT2AALDH1A1MEN1HTT | |
| SCHEMBL17950510 | 0.76 | GPR139 (0.51) | GPR139NPC1SMN1; SMN2MAPTRAB9A | |
| SCHEMBL17950509 | 0.76 | TDP1 (0.42) | SMN1; SMN2MAPTKMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104530037-B | Triazine heterocyclic compound with nematicidal activity and preparation method and application thereof | 华东理工大学 | 2020-12-18 | — | — | CN | disclosed |
| WO-2016116058-A1 | TRIAZINE HETEROCYCLIC COMPOUND WITH NEMATICIDAL ACTIVITY AND PREPARATION METHOD THEREFOR AND USAGE THEREOF | 华东理工大学 | 2016-07-28 | — | — | WO | disclosed |