SCHEMBL17951145

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL28230643	0.90	MAPK1 (0.41)	MAPK1USP2ALDH1A1LMNAEPHX2
	SCHEMBL9929963	0.86	MAP4K4 (0.47)	MAP4K4NAMPTALOX5APFEN1JAK3
	SCHEMBL31124435	0.85	BTK (0.46)	NAMPTGPR119JAK3BTKJAK2
	SCHEMBL31124343	0.85	BTK (0.46)	NAMPTGPR119JAK3BTKJAK2
	SCHEMBL17951124	0.84	JAK2 (0.40)	MAP4K4NAMPTALOX5APFEN1GPR119
	SCHEMBL17951105	0.82	RAB9A (0.40)	ALDH1A1POLBRAB9A
	SCHEMBL19725939	0.82	GPR119 (0.42)	NAMPTGPR119BCHEHTR6
	SCHEMBL6128886	0.82	GPR119 (0.49)	GPR119JAK3BTKJAK1BCHE
	SCHEMBL2728373	0.82	GPR119 (0.49)	GPR119JAK3BTKJAK1BCHE
	SCHEMBL17545832	0.82	GPR119 (0.49)	GPR119JAK3BTKJAK1BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.