SCHEMBL17952107

SCHEMBL17952107

Cc1cc(C)c(N2c3ccc(C#N)c(C#N)c3N(C)[C@@H]2C)c(C)c1

nearest known ligand 0.31

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ AR P10275 5/20 0.31
▸ KDM4E B2RXH2 1/20 0.30
▸ MAPT P10636 1/20 0.30
▸ ALOX15 P16050 1/20 0.30
▸ CASP1 P29466 1/20 0.30
▸ CASP7 P55210 1/20 0.30
▸ HSD17B10 Q99714 1/20 0.30
▸ TDP1 Q9NUW8 1/20 0.30
▸ LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17952104 0.90 AR (0.32) AR
SCHEMBL17952239 0.90 AR (0.31) ARKDM4EMAPTALOX15CASP1
SCHEMBL17952110 0.88 NPSR1 (0.33) ARLMNA
SCHEMBL17952109 0.88 CYP1A2 (0.37) ARMAPTALOX15CASP1CASP7
SCHEMBL17952090 0.87 AR (0.32) AR
SCHEMBL17952094 0.87 AR (0.33) AR
SCHEMBL17952285 0.87 ALDH1A1 (0.31) ARLMNA
SCHEMBL17952091 0.85 AR (0.34) AR
SCHEMBL17952628 0.85 KDM4E (0.32) ARKDM4EMAPTALOX15CASP1
SCHEMBL17952254 0.85 AR (0.32) AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10418569-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-09-17 — — US disclosed
US-20160218303-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-07-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10418569-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, OSBP2 AR 1525/4885KDM4E 4426/4885MAPT 1912/4885
US-20160218303-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OSBP2 AR 1525/4885KDM4E 4426/4885MAPT 1912/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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