Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | TNF | P01375 | 1/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.37 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | TSPO | P30536 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17952892 | 0.89 | PIK3CA (0.42) | PIK3CAIDO1CYP17A1CYP1A2TNF | |
| SCHEMBL21692320 | 0.89 | PIK3CA (0.46) | PIK3CACYP17A1CYP1A2TNFMKNK1 | |
| SCHEMBL25693003 | 0.85 | MEN1 (0.39) | PIK3CAHTR6TSPOMEN1APAF1 | |
| SCHEMBL19238239 | 0.83 | PIK3CA (0.36) | PIK3CACYP17A1CYP1A2TNFMKNK1 | |
| SCHEMBL19238253 | 0.83 | PIK3CA (0.36) | PIK3CACYP17A1CYP1A2TNFMKNK1 | |
| SCHEMBL17952768 | 0.82 | PIK3CA (0.46) | PIK3CACYP17A1CYP1A2TNFMKNK1 | |
| SCHEMBL17952779 | 0.82 | IDO1 (0.41) | IDO1CYP17A1CYP1A2RPS6KA3MAOA | |
| SCHEMBL17952856 | 0.82 | PIK3CA (0.46) | PIK3CACYP17A1CYP1A2TNFMKNK1 | |
| SCHEMBL21692213 | 0.82 | KDM4E (0.41) | PIK3CACYP17A1CYP1A2MKNK1DHODH | |
| SCHEMBL26529480 | 0.81 | NPSR1 (0.38) | PIK3CAHTR6TSPOMEN1APAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3247771-B1 | PYRIDINES AND DERIVATIVES THEREOF AS COMPONENTS FOR USE IN OPTOELECTRONIC COMPONENTS | CYNORA GMBH (DE) | 2020-06-10 | — | — | EP | disclosed |
| US-10544361-B2 | Pyridines and derivatives thereof as components for use in optoelectronic components | CYNORA GMBH (DE) | 2020-01-28 | — | — | US | disclosed |
| WO-2016116517-A1 | PYRIDINES AND DERIVATIVES THEREOF AS COMPONENTS FOR USE IN OPTOELECTRONIC COMPONENTS | CYNORA GMBH (DE) | 2016-07-28 | — | — | WO | disclosed |