Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 2/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | TNF | P01375 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23348023 | 0.90 | MAPK10 (0.40) | PIK3CAMKNK1MAPK10IMPDH2CYP17A1 | |
| SCHEMBL17952787 | 0.89 | PIK3CA (0.42) | PIK3CAMKNK1MAPK10IMPDH2CYP17A1 | |
| SCHEMBL21692320 | 0.88 | PIK3CA (0.46) | PIK3CAMKNK1MAPK10IMPDH2CYP17A1 | |
| SCHEMBL23255440 | 0.88 | KIF11 (0.39) | PIK3CAHTR6DHODHCYP11B1CYP11B2 | |
| SCHEMBL21758173 | 0.88 | CYP11B2 (0.42) | PIK3CACYP17A1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL23347688 | 0.88 | MAPK10 (0.36) | PIK3CAMKNK1MAPK10IMPDH2CYP17A1 | |
| SCHEMBL20613840 | 0.87 | MAPK10 (0.38) | PIK3CAMKNK1MAPK10HTR6CYP1A2 | |
| SCHEMBL26003647 | 0.87 | MEN1 (0.39) | PIK3CAMAPK10IMPDH2HTR6DHODH | |
| SCHEMBL23347946 | 0.86 | MAPK10 (0.39) | PIK3CAMAPK10CYP17A1CYP1A2TNF | |
| SCHEMBL23255422 | 0.86 | CYP11B1 (0.38) | HTR6DHODHCYP19A1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3247771-B1 | PYRIDINES AND DERIVATIVES THEREOF AS COMPONENTS FOR USE IN OPTOELECTRONIC COMPONENTS | CYNORA GMBH (DE) | 2020-06-10 | — | — | EP | disclosed |
| US-10544361-B2 | Pyridines and derivatives thereof as components for use in optoelectronic components | CYNORA GMBH (DE) | 2020-01-28 | — | — | US | disclosed |
| WO-2016116517-A1 | PYRIDINES AND DERIVATIVES THEREOF AS COMPONENTS FOR USE IN OPTOELECTRONIC COMPONENTS | CYNORA GMBH (DE) | 2016-07-28 | — | — | WO | disclosed |