Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | RAC2 | P15153 | 1/20 | 0.39 |
| ▸ | RAC3 | P60763 | 1/20 | 0.39 |
| ▸ | CDC42 | P60953 | 1/20 | 0.39 |
| ▸ | RAC1 | P63000 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.33 |
| ▸ | EDNRB | P24530 | 1/20 | 0.33 |
| ▸ | EDNRA | P25101 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17952803 | 1.00 | KDM4E (0.44) | KDM4EL3MBTL1ATMRAC2RAC3 | |
| SCHEMBL15159276 | 0.95 | ATM (0.44) | KDM4EL3MBTL1ATMRAC2RAC3 | |
| SCHEMBL20201846 | 0.92 | KDM4E (0.48) | KDM4EL3MBTL1ATMRAC2RAC3 | |
| SCHEMBL20201843 | 0.92 | KDM4E (0.48) | KDM4EL3MBTL1ATMRAC2RAC3 | |
| SCHEMBL612850 | 0.92 | KDM4E (0.52) | KDM4EL3MBTL1ATMCHRNB4CHRNA3 | |
| SCHEMBL17952933 | 0.89 | L3MBTL1 (0.44) | KDM4EL3MBTL1ATMRAC2RAC3 | |
| SCHEMBL17952900 | 0.89 | L3MBTL1 (0.44) | KDM4EL3MBTL1ATMRAC2RAC3 | |
| SCHEMBL15159275 | 0.89 | KDM4E (0.39) | KDM4EL3MBTL1ATMRAC2RAC3 | |
| SCHEMBL17952980 | 0.89 | KDM4E (0.47) | KDM4EL3MBTL1ATMRAC2RAC3 | |
| SCHEMBL17952956 | 0.89 | KDM4E (0.47) | KDM4EL3MBTL1ATMRAC2RAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3247771-B1 | PYRIDINES AND DERIVATIVES THEREOF AS COMPONENTS FOR USE IN OPTOELECTRONIC COMPONENTS | CYNORA GMBH (DE) | 2020-06-10 | — | — | EP | disclosed |
| US-10544361-B2 | Pyridines and derivatives thereof as components for use in optoelectronic components | CYNORA GMBH (DE) | 2020-01-28 | — | — | US | disclosed |
| WO-2016116517-A1 | PYRIDINES AND DERIVATIVES THEREOF AS COMPONENTS FOR USE IN OPTOELECTRONIC COMPONENTS | CYNORA GMBH (DE) | 2016-07-28 | — | — | WO | disclosed |