SCHEMBL612850

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL11987869	0.95	KDM4E (0.47)	KDM4EATML3MBTL1CHRNB4CHRNA3
	SCHEMBL11895266	0.93	KDM4E (0.46)	KDM4EATML3MBTL1CHRNB4CHRNA3
	SCHEMBL17952803	0.92	KDM4E (0.44)	KDM4EATML3MBTL1CHRNB4CHRNA3
	SCHEMBL17952804	0.92	KDM4E (0.44)	KDM4EATML3MBTL1CHRNB4CHRNA3
	SCHEMBL10024691	0.92	L3MBTL1 (0.48)	KDM4EATML3MBTL1CHRNB4CHRNA3
	SCHEMBL29511975	0.92	L3MBTL1 (0.48)	KDM4EATML3MBTL1CHRNB4CHRNA3
	SCHEMBL21453879	0.90	L3MBTL1 (0.47)	KDM4EATML3MBTL1CHRNB4CHRNA3
	SCHEMBL523406	0.90	KDM4E (0.58)	KDM4EATML3MBTL1CYP11B2CYP11B1
	SCHEMBL10015252	0.89	KDM4E (0.48)	KDM4EATML3MBTL1CHRNB4CHRNA3
	SCHEMBL16089816	0.89	KDM4E (0.42)	KDM4EATML3MBTL1CHRNB4CHRNA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.