Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | P2RX4 | Q99571 | 11/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17952901 | 0.87 | FAAH (0.38) | CHRNB4CHRNA3P2RX4MAPTSMN1; SMN2 | |
| SCHEMBL17952968 | 0.87 | MKNK1 (0.37) | CHRNB4CHRNA3P2RX4MAPTSMN1; SMN2 | |
| SCHEMBL11987866 | 0.84 | KDM4E (0.37) | CHRNB4CHRNA3LRRK2KDM4E | |
| SCHEMBL12620329 | 0.82 | ATM (0.40) | P2RX4MAPTSMN1; SMN2NPSR1KDM4E | |
| SCHEMBL23625962 | 0.80 | P2RX4 (0.39) | P2RX4MAPTSMN1; SMN2NPSR1KDM4E | |
| SCHEMBL17952816 | 0.80 | CHRNB4 (0.44) | CHRNB4CHRNA3NPSR1ALDH1A1 | |
| SCHEMBL17952736 | 0.80 | CYP11B1 (0.35) | P2RX4MAPTSMN1; SMN2NPSR1KDM4E | |
| SCHEMBL12620367 | 0.80 | CYP2A6 (0.44) | KDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL22569128 | 0.80 | P2RX4 (0.43) | P2RX4MAPTSMN1; SMN2NPSR1 | |
| SCHEMBL12620316 | 0.80 | CYP2A6 (0.44) | KDM4EALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10544361-B2 | Pyridines and derivatives thereof as components for use in optoelectronic components | CYNORA GMBH (DE) | 2020-01-28 | — | — | US | disclosed |
| WO-2016116517-A1 | PYRIDINES AND DERIVATIVES THEREOF AS COMPONENTS FOR USE IN OPTOELECTRONIC COMPONENTS | CYNORA GMBH (DE) | 2016-07-28 | — | — | WO | disclosed |