Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20383134 | 0.89 | ALDH1A1 (0.46) | FAAHALDH1A1HSP90AA1PKMHTT | |
| SCHEMBL21927181 | 0.89 | BACE1 (0.42) | GABRG2GABRB3GABRA5GABRA3CYP11B2 | |
| SCHEMBL17952807 | 0.87 | CHRNB4 (0.38) | ALDH1A1CHRNB4CHRNA3MAPTSMN1; SMN2 | |
| SCHEMBL21928202 | 0.85 | CYP11B2 (0.42) | FAAHALDH1A1HSP90AA1PKMHTT | |
| SCHEMBL17952968 | 0.84 | MKNK1 (0.37) | FAAHMGLLCHRNB4CHRNA3CYP11B2 | |
| SCHEMBL16271053 | 0.81 | ALDH1A1 (0.37) | FAAHALDH1A1HSP90AA1PKMHTT | |
| SCHEMBL19269440 | 0.81 | GSK3B (0.35) | FAAHALDH1A1HSP90AA1PKMHTT | |
| SCHEMBL12620367 | 0.81 | CYP2A6 (0.44) | ALDH1A1GRM5CYP11B2CYP11B1MKNK1 | |
| SCHEMBL12620316 | 0.81 | CYP2A6 (0.44) | ALDH1A1GRM5CYP11B2CYP11B1MKNK1 | |
| SCHEMBL21578688 | 0.81 | FAAH (0.37) | FAAHALDH1A1HSP90AA1PKMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3247771-B1 | PYRIDINES AND DERIVATIVES THEREOF AS COMPONENTS FOR USE IN OPTOELECTRONIC COMPONENTS | CYNORA GMBH (DE) | 2020-06-10 | — | — | EP | disclosed |
| US-10544361-B2 | Pyridines and derivatives thereof as components for use in optoelectronic components | CYNORA GMBH (DE) | 2020-01-28 | — | — | US | disclosed |
| WO-2016116517-A1 | PYRIDINES AND DERIVATIVES THEREOF AS COMPONENTS FOR USE IN OPTOELECTRONIC COMPONENTS | CYNORA GMBH (DE) | 2016-07-28 | — | — | WO | disclosed |