Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | SMO | Q99835 | 2/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 5/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17952976 | 0.86 | ASIC3 (0.44) | ASIC3PIM1SMOTGFBR1CYP1A2 | |
| SCHEMBL6130724 | 0.83 | ASIC3 (0.53) | ASIC3PIM1CYP11B1TGFBR1CYP1A2 | |
| SCHEMBL29854571 | 0.82 | ASIC3 (0.61) | ASIC3PIM1SMOTGFBR1MAP4K4 | |
| SCHEMBL24291931 | 0.82 | ASIC3 (0.61) | ASIC3PIM1SMOTGFBR1MAP4K4 | |
| SCHEMBL17694751 | 0.82 | ASIC3 (0.61) | ASIC3PIM1SMOTGFBR1MAP4K4 | |
| SCHEMBL21692157 | 0.82 | ASIC3 (0.65) | ASIC3PIM1SMOTGFBR1KDM4E | |
| SCHEMBL21012595 | 0.81 | KDM4E (0.50) | CYP11B1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL6356563 | 0.81 | KDM4E (0.50) | CYP11B1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL27757723 | 0.81 | MAPT (0.52) | ASIC3PIM1SMOCYP1A2CYP3A4 | |
| SCHEMBL29578028 | 0.80 | ASIC3 (0.63) | ASIC3PIM1SMOTGFBR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3247771-B1 | PYRIDINES AND DERIVATIVES THEREOF AS COMPONENTS FOR USE IN OPTOELECTRONIC COMPONENTS | CYNORA GMBH (DE) | 2020-06-10 | — | — | EP | disclosed |
| US-10544361-B2 | Pyridines and derivatives thereof as components for use in optoelectronic components | CYNORA GMBH (DE) | 2020-01-28 | — | — | US | disclosed |
| WO-2016116517-A1 | PYRIDINES AND DERIVATIVES THEREOF AS COMPONENTS FOR USE IN OPTOELECTRONIC COMPONENTS | CYNORA GMBH (DE) | 2016-07-28 | — | — | WO | disclosed |