Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASIC3 | Q9UHC3 | 2/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 5/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.38 |
| ▸ | SMO | Q99835 | 2/20 | 0.37 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.36 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.36 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17952946 | 0.86 | ASIC3 (0.47) | ASIC3PIM1TGFBR1CYP1A2CYP3A4 | |
| SCHEMBL5115970 | 0.84 | CYP2A6 (0.46) | TGFBR1CYP1A2HTR1AHTR7 | |
| SCHEMBL16484524 | 0.84 | CYP2A6 (0.46) | TGFBR1CYP1A2HTR1AHTR7 | |
| SCHEMBL30109153 | 0.84 | CYP2A6 (0.46) | TGFBR1CYP1A2HTR1AHTR7 | |
| SCHEMBL6130724 | 0.84 | ASIC3 (0.53) | ASIC3PIM1TGFBR1CYP1A2CYP3A4 | |
| SCHEMBL5102763 | 0.83 | CYP2A6 (0.44) | TGFBR1CYP1A2HTR1AHTR7 | |
| SCHEMBL5109020 | 0.82 | KIF11 (0.40) | ASIC3PIM1TGFBR1CYP1A2CYP3A4 | |
| SCHEMBL18253256 | 0.81 | KMO (0.50) | ASIC3CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL12408985 | 0.81 | ASIC3 (0.53) | ASIC3PIM1TGFBR1HSD17B1HSD17B2 | |
| SCHEMBL28116354 | 0.81 | ASIC3 (0.53) | ASIC3PIM1TGFBR1HSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10544361-B2 | Pyridines and derivatives thereof as components for use in optoelectronic components | CYNORA GMBH (DE) | 2020-01-28 | — | — | US | disclosed |
| WO-2016116517-A1 | PYRIDINES AND DERIVATIVES THEREOF AS COMPONENTS FOR USE IN OPTOELECTRONIC COMPONENTS | CYNORA GMBH (DE) | 2016-07-28 | — | — | WO | disclosed |